PMID: 7538150Feb 1, 1995Paper

Latex agglutination for rapid detection of Pseudomonas pseudomallei antigen in urine of patients with melioidosis

Journal of Clinical Pathology
M D SmithN J White

Abstract

A latex agglutination test for the detection of Pseudomonas pseudomallei antigen in urine was evaluated for the rapid diagnosis of melioidosis. With unconcentrated urine, antigen was detected in only 18% of patients with melioidosis overall. However, when urine was concentrated 100-fold, antigen was detected in 47% overall and in 67% of patients with septicaemia or disseminated infection, in whom a rapid diagnosis is most important. The specificity of the test was 100%. These results compared favourably with an enzyme immunoassay. This latex agglutination test is a simple, rapid and highly specific method of diagnosing melioidosis, and will be particularly useful in areas with limited laboratory facilities.

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Citations

Dec 1, 1995·FEMS Immunology and Medical Microbiology·L V PhungI Yano
Feb 16, 2000·Acta Tropica·S SirisinhaY Suputtamongkol
Sep 7, 2007·Journal of Clinical Microbiology·Premjit AmornchaiSharon J Peacock
Nov 28, 2002·Journal of Clinical Microbiology·Peter LoweRobert Norton
Oct 12, 2005·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M V JesudasonG Sridharan
Dec 25, 2007·Applied and Environmental Microbiology·Kyoung-Hee ChoiHerbert P Schweizer
Apr 1, 1996·Journal of Clinical Microbiology·A AnuntagoolS Sirisinha

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