PMID: 2497890Apr 22, 1989Paper

Latex agglutination test for diagnosing pneumococcal pneumonia in children in developing countries

BMJ : British Medical Journal
K P O'NeillB M Greenwood

Abstract

To prepare and assess the sensitivity and specificity of a latex agglutination test specific for the serotype of antigen in diagnosing pneumococcal pneumonia in Gambian children. Comparison of agglutination test specific for serotype with culture of blood and lung aspirates, countercurrent immunoelectrophoresis, and commercial latex agglutination tests in diagnosing pneumococcal pneumonia. Cross reaction studies and investigation of 102 control children to determine specificity of agglutination test specific for serotype. General medical ward of Medical Research Council laboratories, The Gambia. 101 Gambian children aged between 2 months and 10 years admitted with severe pneumonia. Serum samples were boiled and treated with edetic acid, and urine samples were boiled and concentrated 25 times before testing. A latex agglutination test specific for the serotype of pneumococcal antigen that is sensitive and highly specific for detecting pneumococcus in the urine of patients with pneumococcal pneumonia. Concentrated urine samples from 16 of the 21 children (76%) with pneumococcal pneumonia established by results of culture of blood or lung aspirates gave a positive result with the agglutination test specific for serotype, whereas o...Continue Reading

References

Feb 1, 1975·Journal of Clinical Pathology·P Tugwell, B M Greenwood
Mar 1, 1976·Annals of Internal Medicine·J D Coonrod, D P Drennan
Jun 6, 1987·Lancet·T GottliebS Naraqi
May 21, 1988·Lancet
Jun 1, 1985·Journal of Clinical Microbiology·G A Weinberg, G A Storch
Mar 1, 1986·Pediatric Infectious Disease·F Shann
Apr 12, 1984·The New England Journal of Medicine·J ChretienA Woolcock

❮ Previous
Next ❯

Citations

Mar 1, 1992·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·O RuuskanenM Leinonen
Jan 1, 1996·Diagnostic Microbiology and Infectious Disease·L H HarrisonR R Arthur
Mar 7, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·E Vuori-Holopainen, H Peltola
Dec 4, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Ian C MichelowGeorge H McCracken
Feb 12, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Anja M Werno, David R Murdoch
Sep 22, 2000·Archives of Disease in Childhood·H ClementsC J Linton
Jul 1, 1992·Infection·W G Boersma, Y Holloway
Mar 18, 2015·Tropical Medicine & International Health : TM & IH·Effua UsufChristian Bottomley
Sep 1, 1991·The Journal of Infection·M Farrington, D Rubenstein
Apr 13, 2005·Seminars in Pediatric Infectious Diseases·Miguel Cashat-CruzMónica Mendoza-Azpiri
Mar 1, 1997·The Pediatric Infectious Disease Journal·J García-de-Lomas, D Navarro
May 1, 1996·The Pediatric Infectious Disease Journal·T J O'DempseyB Greenwood
Feb 20, 1998·The Pediatric Infectious Disease Journal·S UsenB Greenwood
Aug 17, 2000·Annals of Tropical Paediatrics·R L FooC M Parry

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antibodies: Agglutination

Antibody-mediated agglutination is the clumping of cells in the presence of antibody, which binds multiple cells together. This enhances the clearance of pathogens. Find the latest research on antibody-mediated agglutination here.

Bacterial Pneumonia

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Bacterial Pneumonia (ASM)

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.