Abstract
The present study aimed to investigate to what extent glove powders of different origins and brands bind and release latex allergens. One mineral talc and five cornstarch powders were used. The allergenic material was sap of Hevea brasiliensis. The powders were incubated together with the natural rubber latex sap, and four series of experiments were performed. The talc showed the highest tendency to bind isotope-labeled proteins. When incubated with a latex allergen solution, it reduced free allergen from 100 to 2 units/ml compared to a reduction to 70-98 units/ml for the cornstarch powders. In contrast to the nonstable binding of allergen to cornstarch, the binding to talc was irreversible. The allergen bound to talc was allergenically intact and, when incubated with serum, reduced the concentration of free IgE antibody to latex to 10% of the initial level. Mineral talc had a high capacity to bind latex allergens firmly. In contrast, cornstarch captured the latex allergen, but the binding seemed less pronounced and was unstable. The replacement of talc by cornstarch as glove-donning powder has coincided with the rapid increase in latex allergy. Mineral talc is heavy and only transiently airborne. Could this difference between ...Continue Reading
References
Nov 1, 1992·Archives of Surgery·D Beezhold, W C Beck
Mar 1, 1992·The Journal of Allergy and Clinical Immunology·D JaegerX Baur
Oct 1, 1988·Contact Dermatitis·K WrangsjöI G Axelsson
Apr 1, 1980·Allergy·H Schröder, L Yman
Jun 1, 1980·Archives of Surgery·T W Tolbert, J L Brown
Oct 1, 1995·The Journal of Allergy and Clinical Immunology·G BrugnamiG Abbritti
Apr 1, 1995·Allergy·M LundbergS G Johansson
Jun 1, 1994·The Journal of Allergy and Clinical Immunology·S M TarloM C Swanson
Jul 1, 1994·The Journal of Allergy and Clinical Immunology·B L CharousJ W Yunginger
Aug 1, 1994·The Journal of Allergy and Clinical Immunology·J E Slater
Sep 1, 1994·The Journal of Allergy and Clinical Immunology·M C SwansonC E Reed
Apr 1, 1994·The Journal of Allergy and Clinical Immunology·V J TomazicR G Hamilton
May 1, 1994·The Journal of Allergy and Clinical Immunology·J W YungingerL W Hunt
Mar 1, 1996·Archives of Dermatology·J S Taylor, P Praditsuwan
May 1, 1996·The Journal of Allergy and Clinical Immunology·A AkasawaY Lin
Jan 1, 1996·Allergy·K Wrangsjö, M Lundberg
Aug 1, 1996·The Journal of Allergy and Clinical Immunology·D K HeilmanJ W Yunginger
Sep 1, 1996·Allergy·K TurjanmaaT Palosuo
Oct 1, 1963·The Biochemical Journal·F C GREENWOODJ S GLOVER
Citations
Jun 5, 1999·American Journal of Contact Dermatitis : Official Journal of the American Contact Dermatitis Society·J D GuinK Caplinger
Jun 28, 2002·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Didier G Ebo, Wim J Stevens
May 28, 2004·Journal of Immunoassay & Immunochemistry·Vesna J Tomazic-JezicBeatriz A Sanchez
Feb 12, 1999·Journal - Canadian Dental Association = Journal De L'Association Dentaire Canadienne·M D Charendoff
Aug 24, 1999·Plastic and Reconstructive Surgery·P J Chandler
May 15, 2001·Occupational and Environmental Medicine·N ChaiearP S Burge
Jul 13, 2011·Journal of Allergy·Arja ViinanenKaija Lammintausta
Jan 22, 2003·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·J BarbaraF Leynadier
Aug 4, 2015·International Journal of Biological Macromolecules·Thanida ArpornwichanopPramuan Tangboriboonrat
Jun 16, 2004·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·J BarbaraF Leynadier
Jul 16, 2003·Allergy·S La GruttaG Passalacqua
Dec 17, 2003·Allergy·R A M LopesR L Zollner
Aug 3, 2002·Acta Clinica Belgica·D G Ebo, W J Stevens
Aug 19, 2004·AORN Journal·Rosimeire Aparecida Mendes LopesRicardo de Lima Zollner
Apr 23, 2003·AORN Journal·Denise M KorniewiczKevin P O'Connell
Jun 19, 2013·Carbohydrate Polymers·Nuttakun KanjanathawornPramuan Tangboriboonrat
Mar 17, 2000·The Journal of Allergy and Clinical Immunology·M GroteR Reichelt
Nov 24, 1999·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·A W Frankland
Dec 3, 2008·Journal of Food Protection·Rohan AmeratungaGreg Simmons
Oct 2, 2020·Contact Dermatitis·Nils HamneriusAnn Pontén
Sep 20, 2001·American Journal of Otolaryngology·R WeberP H Toffel