Lay people's understanding of and preference against the word "mutation"

American Journal of Medical Genetics. Part a
Celeste M ConditRoxanne Parrott

Abstract

Lay understandings of the term "mutation" are explored using three methodologies and three population bases. A community based sample (n = 848) employing a written survey to assess knowledge and understanding indicated good lay understanding of the basic concept of mutation. However, lay people associated mutation with reproductive outcomes, but not with changes in genes across the life span. A student sample (n = 241) employed a written survey to assess connotations of the term mutation. It showed a strong negative response to mutation. A community based sample (n = 120) employing focus groups also showed strong negative reactions to the term mutation and rejection of use of the term mutation in public service announcements (PSAs). The term variation had better response and is recommended as an alternative in genetic counseling and public media.

References

Jun 5, 1998·Annual Review of Public Health·B A IsraelA B Becker
Dec 26, 2001·Human Mutation·Richard G H Cotton
Dec 26, 2001·Human Mutation·Celeste M ConditEnid Sefcovic
Mar 26, 2003·American Journal of Medical Genetics. Part a·Bonnie Jeanne BatySara Marie Ellis
Sep 23, 2003·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Celeste ConditTina M Harris

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Citations

Feb 28, 2006·Journal of Genetic Counseling·J HodgsonC Lambert
Mar 3, 2007·Journal of Genetic Counseling·Lisa KesslerChanita Hughes Halbert
May 4, 2007·Journal of Genetic Counseling·Rachel A Smith
Jun 1, 2010·Journal of Genetic Counseling·Robert L Klitzman
Sep 9, 2005·Health Education & Behavior : the Official Publication of the Society for Public Health Education·Catharine WangSharon L R Kardia
May 29, 2009·Genetic Testing and Molecular Biomarkers·Claire E WakefieldNadine A Kasparian
Sep 20, 2007·Nature Reviews. Genetics·Celeste M Condit
Jan 23, 2010·Clinical Genetics·C M Condit
Jul 6, 2005·Clinical Genetics·C Condit, B Bates
Mar 6, 2019·PloS One·Fernando Blanco, Helena Matute
Apr 25, 2006·Journal of Clinical Nursing·Heather SkirtonMarlene Z Cohen
Nov 28, 2016·Journal of Cancer Education : the Official Journal of the American Association for Cancer Education·Yelena P WuSancy A Leachman
Apr 23, 2015·American Journal of Medical Genetics. Part a·Susan Brown TrinidadWylie Burke

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