Layer-by-layer modification of high surface curvature nanoparticles with weak polyelectrolytes using a multiphase solvent precipitation process

Journal of Colloid and Interface Science
Ashvin T NagarajaMichael J McShane

Abstract

The layer-by-layer modification of ≈5 nm mercaptocarboxylic acid stabilized gold nanoparticles was studied in an effort to illustrate effective means to overcome practical issues in handling and performing surface modification of such extremely small materials. To accomplish this, each layer deposition cycle was separated into a multi-step process wherein solution pH was controlled in two distinct phases of polyelectrolyte adsorption and centrifugation. Additionally, a solvent precipitation step was introduced to make processing more amenable by concentrating the sample and exchanging solution pH before ultracentrifugation. The pH-dependent assembly on gold nanoparticles was assessed after each layer deposition cycle by monitoring the plasmon peak absorbance location, surface charge, and the percentage of nanoparticles recovered. The selection of solution pH during the adsorption phase was found to be a critical parameter to enhance particle recovery and maximize surface charge when coating with weak polyelectrolytes. One bilayer was deposited with a high yield and the modified particles exhibited enhanced colloidal stability across a broad pH range and increased ionic strength. These findings support the adoption of this multi...Continue Reading

References

Nov 4, 2000·Physical Review Letters·K K Kunze, R R Netz
Dec 6, 2002·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·David I Gittins, Frank Caruso
Oct 7, 2003·Annual Review of Biomedical Engineering·Jennifer L West, Naomi J Halas
Nov 11, 2003·Biomacromolecules·Susan E Burke, Christopher J Barrett
Sep 7, 2005·Langmuir : the ACS Journal of Surfaces and Colloids·Elvira TjiptoFrank Caruso
Jun 14, 2006·Langmuir : the ACS Journal of Surfaces and Colloids·Tatjana MauserGleb B Sukhorukov
Apr 27, 2007·Analytical Chemistry·Wolfgang HaissDavid G Fernig
Jan 31, 2008·Langmuir : the ACS Journal of Surfaces and Colloids·Annie DorrisR Bruce Lennox
Sep 8, 2009·Nature Nanotechnology·Yongdong Jin, Xiaohu Gao
Dec 22, 2009·Physical Chemistry Chemical Physics : PCCP·Xiao Gong, Changyou Gao
Feb 17, 2010·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·R A Sperling, W J Parak
May 7, 2013·Annual Review of Biomedical Engineering·Gang BaoSheng Tong
May 11, 2013·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Hamed LarouiDidier Merlin
May 21, 2013·Physical Chemistry Chemical Physics : PCCP·Xiao Gong
Jul 31, 2013·Journal of Colloid and Interface Science·Patricia Taladriz-BlancoSalvatore Sortino
Nov 19, 2013·Genes & Development·Ian Y WongMehmet Toner
Feb 18, 2014·International Journal of Nanomedicine·Vanna SannaMario Sechi

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Citations

Dec 15, 2016·Chemical Reviews·Joseph J RichardsonFrank Caruso

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