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LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

Bioinformatics

Nov 3, 2016

Jie ZhengBenjamin M Neale

Abstract

LD score regression is a reliable and efficient method of using genome-wide association study (GWAS) summary-level results data to estimate the SNP heritability of complex traits and diseases, partition this heritability into functional categories, and estimate the genetic correlation b...read more

Mentioned in this Paper

EAF2 gene
Linkage Disequilibrium
Screening Generic
Sample Size
Uptake
Autosomal Recessive Hereditary Disorder
Meta-Analysis (Publications)
Genetic Predisposition to Disease
Public Health Practice
Genome-Wide Association Study
23
320
1
Paper Details
References
  • References50
  • Citations85
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  • References50
  • Citations85
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LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

Bioinformatics

Nov 3, 2016

Jie ZhengBenjamin M Neale

PMID: 27663502

DOI: 10.1093/bioinformatics/btw613

Abstract

LD score regression is a reliable and efficient method of using genome-wide association study (GWAS) summary-level results data to estimate the SNP heritability of complex traits and diseases, partition this heritability into functional categories, and estimate the genetic correlation b...read more

Mentioned in this Paper

EAF2 gene
Linkage Disequilibrium
Screening Generic
Sample Size
Uptake
Autosomal Recessive Hereditary Disorder
Meta-Analysis (Publications)
Genetic Predisposition to Disease
Public Health Practice
Genome-Wide Association Study
23
320
1

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  • Citations85
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