LDH isoenzyme pattern in a meningioma with pulmonary metastases

The Journal of Pathology
I V AllenC A Gleadhill


The case is presented of an intraspinal meningioma in a 14-yr-old female. After surgical exploration pulmonary metastases became apparent. At necropsy the tumour had increased proportions of the cathodal isoenzymes LDH-4 and 5. This pattern has previously been observed in malignant meningiomas and may be used at the time of biopsy to assess malignancy.


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