PMID: 9650693Jul 3, 1998Paper

LE or not LE--that is the question: an unsuccessful attempt to separate lymphocytic infiltration from the spectrum of discoid lupus erythematosus

The American Journal of Dermatopathology
W WeyersI Weyers

Abstract

Lymphocytic infiltration of the skin (LIS) has been claimed to be a distinct entity that differs from discoid lupus erythematosus (DLE) by the lack of epidermal changes, negative immunofluorescence tests, and differences in the composition of the inflammatory cell infiltrate. In studies that sought to distinguish both conditions, however, cases of established lupus erythematosus without epidermal involvement have not been considered. We studied 72 patients with the clinical and histopathologic diagnosis of either LIS or DLE in regard to the same clinical, histopathologic, immunofluorescence, and immunohistochemical criteria. No significant differences were noted between cases with and without epidermal involvement on the one hand and between cases with and without immunofluorescence or clinical findings suggestive of lupus erythematosus on the other. Based on our findings, it is not possible to separate LIS from the spectrum of DLE.

References

Jul 1, 1975·The Journal of Investigative Dermatology·D L Tuffanelli
Aug 1, 1991·The American Journal of Dermatopathology·J Toonstra, S C van der Putte
Aug 1, 1990·The American Journal of Dermatopathology·F FacchettiV J Desmet
Aug 1, 1987·The Journal of Investigative Dermatology·Y T KonttinenM Malmström
Sep 1, 1986·Journal of the American Academy of Dermatology·B S AndrewsP Ross
Aug 1, 1969·Archives of Dermatology·B L Krieger
May 1, 1984·The British Journal of Dermatology·R WillemzeC J Meijer
Aug 1, 1984·Journal of the American Academy of Dermatology·D A Weigand
Nov 1, 1996·The Australasian Journal of Dermatology·M S LeeS Kossard
May 1, 1957·The British Journal of Dermatology·C D CALNAN

❮ Previous
Next ❯

Citations

Jun 17, 2006·Dermatology : International Journal for Clinical and Investigative Dermatology·Dan LipskerBernard Cribier
Oct 12, 2012·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·G WagnerM M Sachse
Aug 18, 1999·Immunological Reviews·O T ChanM J Shlomchik
Nov 17, 2007·Journal of the European Academy of Dermatology and Venereology : JEADV·U Wollina, G Hansel
Nov 10, 2004·International Journal of Dermatology·Charoen ChoonhakarnJaruwan Chaivoramukul
Jun 10, 2006·Lupus·M TeixeiraM Selores
Sep 17, 2004·The Journal of Dermatological Treatment·A HafejeeI H Coulson
Jan 28, 2006·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·A KuhnN J Neumann
Sep 7, 2000·The Journal of Immunology : Official Journal of the American Association of Immunologists·B LiangM J Mamula
Aug 12, 2003·Arthritis and Rheumatism·Macrene R Alexiades-ArmenakasAndrew G Franks
Aug 14, 1999·The American Journal of Dermatopathology·H Ruiz, J L Sánchez
Nov 25, 2003·The American Journal of Dermatopathology·Wolfgang WeyersImke Weyers
Dec 15, 2005·Advances in Dermatology·Karla S DraftRosalie Elenitsas
Jan 24, 2009·Autoimmunity Reviews·Annegret KuhnGisela Bonsmann

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Verhandlungen der Deutschen Gesellschaft für Pathologie
M Bonczkowitz, W Weyers
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
Doulat Rai BajajBhajan Lal Matlani
Giornale Italiano Di Dermatologia E Venereologia : Organo Ufficiale, Società Italiana Di Dermatologia E Sifilografia
R CecchiA Giomi
© 2022 Meta ULC. All rights reserved