Lead exposure is associated with risk of impaired coagulation in preschool children from an e-waste recycling area.

Environmental Science and Pollution Research International
Zhijun ZengXijin Xu

Abstract

Environmental lead exposure leads to various deleterious effects on multiple organs and systems, including the hematopoietic system. To explore the effects of lead exposure on platelet indices in preschool children from an informal, lead-contaminated electronic waste (e-waste) recycling area, we collected venous blood samples from 466 preschool children (331 from an e-waste area (Guiyu) and 135 from a non-e-waste area (Haojiang)). Child blood lead levels (BLLs) were determined by graphite furnace atomic absorption spectrophotometry, while platelet indices were quantified using a Sysmex XT-1800i hematology analyzer. Higher blood lead levels are observed in e-waste lead-exposed preschool children. Significant relationships between high blood lead levels (exceeding current health limits) and elevated platelet count (PLT), plateletcrit (PCT), mean platelet volume (MPV), and platelet large cell ratio (P-LCR) were also uncovered. Furthermore, the median PLT and PCT levels of children from the exposed group both exceeded the respective recommended maximum reference range value, whereas the reference group did not. Location of child residence in Guiyu and BLLs were both risk factors related to platelet indices. These results suggest th...Continue Reading

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Citations

Feb 15, 2020·Environmental Science and Pollution Research International·Shaocheng ZhangXijin Xu
Feb 20, 2020·Environmental Science and Pollution Research International·Saeeda HussainMuhammad Tariq Zahid
Jun 4, 2020·Biological Trace Element Research·Liliana Carranza-LopezJesus Olivero-Verbel
Sep 27, 2020·International Journal of Molecular Sciences·Pablo ScharfSandra Helena Poliselli Farsky
Nov 25, 2020·Neural Regeneration Research·Jian-Zhu BoYan-Shu Zhang
Feb 13, 2021·Toxicology and Applied Pharmacology·Fateme KooshkiJafar Hasanzadeh
May 26, 2021·Environmental Science and Pollution Research International·Guangcan ChenXijin Xu
Jul 24, 2021·Environmental Science and Pollution Research International·Carlos Alberto de AlbuquerqueValquíria Claret Dos Santos

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