PMID: 16612488Apr 14, 2006Paper

Lead levels and cognitive abilities in Peruvian children

Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina
Johann M Vega-DienstmaierJorge Castro-Morales

Abstract

To study the relationship between blood lead levels and cognitive abilities of children exposed to this metal. This is a cross-sectional study that included 134 children aged 6 to 8.5 years old from 3 schools with different risks of lead exposure located in El Callao (Peru). Cognitive assessments were made by means of the Graphic Test of Reasoning (GTR) and the Kohs Block Design Test (KBDT). Blood lead levels and other laboratory tests were performed. Children with lead > 10 ug/dl presented greater prevalence of low scores in the Graphic Test of Reasoning (18.9% vs. 7.1%, p = 0.049) and in the Kohs Block Design Test (KBDT) (39.6% vs. 18.6%, p = 0.01) compared with those with lower lead blood levels. A deficit of 1 category in the Graphic Test of Reasoning was associated with an increase in lead blood level of 16.78 ug/dl (assuming a linear relationship) and from 1 to 5.19 ug/dl (logarithmic model). For each 10 ug/dl of increase in lead levels, the Kohs Block Design Test decreases in 6.24 units (12.91 in males and 0.216 in females) (linear model), and an increase from 1 to 10 ug/dl corresponds to a drop of 16.44 points in the Kohs Block Design Test (31.19 in males and 3.98 in females) (logarithmic model). Considering the Graphic...Continue Reading

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Citations

May 4, 2010·Annual Review of Nutrition·Katarzyna Kordas
Apr 1, 2010·Lipids in Health and Disease·Johny C Ponce-CanchihuamánMarco A Juárez-Oropeza
Apr 8, 2010·Neuroscience Letters·Zhaoming ZhongYi Che
Dec 19, 2008·Chemosphere·Antonio Trejo-AcevedoIván N Pérez-Maldonado
Jul 3, 2013·International Journal of Psychology : Journal International De Psychologie·Kim T FergusonGary W Evans
Oct 6, 2010·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Devon L GrahamMichael T Williams
Feb 6, 2017·Environment International·Kelly Polido Kaneshiro OlympioEtelvino José Henriques Bechara
Dec 17, 2014·Environmental Health Perspectives·Amalia LabordePhilip J Landrigan
Dec 31, 2019·Biochemistry and Biophysics Reports·Mohammad Nasiruddin RanaMd Atiar Rahman
Jun 16, 2021·Environmental Science and Pollution Research International·Serve HeidariFatemeh Rajati
Sep 2, 2021·Saudi Journal of Biological Sciences·Mohammad Nasiruddin RanaArwa A Makki

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