Lead poisoning in Nile tilapia (Oreochromis niloticus): oxidant and antioxidant relationship

Environmental Monitoring and Assessment
Mahmoud Tanekhy

Abstract

Selenium and vitamin E are very effective antioxidant agents which play important roles in improving and development of aquaculture sector. This study was conducted to determine the protective and treatment effects of vitamin E and selenium against lead toxicity. Administration of both vitamin E and selenium ameliorated the adverse effects of lead acetate toxicity through significant increase in hemoglobin, packed cell volume, RBC count, WBC count, and lymphocytes compared to lead acetate-exposed groups especially after the 10th week. Also, it is revealed that severe decrease of total protein, calcium, phosphorous, and magnesium in lead acetate intoxicated group. On contrary, significant increase of blood parameters upon addition of vitamin E and selenium combined with/without lead. On the other hand, insignificant decreases of sAST, sALT, urea, and creatinine in group fed on vitamin E and selenium, while increase in lead acetate intoxicated group. Lead acetate caused increasing of lipid peroxidation level (malondialdehyde) and decreasing of superoxide dismutase activity and reduced glutathione level. From these results, it is concluded that exposure to lead acetate is considered as hepatotoxic environmental pollutant. Exposure...Continue Reading

References

Jan 1, 1982·Annals of the New York Academy of Sciences·F HaourJ P Mather
Jan 21, 1995·Lancet·M Meydani
Jul 1, 1994·The Proceedings of the Nutrition Society·G W Burton
Nov 10, 2001·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·A R Meki, A A Hussein
Dec 18, 2001·Journal of Applied Toxicology : JAT·N BatraM P Bansal
Apr 8, 2003·Life Sciences·Göksel SenerGül Ayanoğlu-Dülger
Jul 1, 1957·American Journal of Clinical Pathology·S REITMAN, S FRANKEL
Feb 3, 2006·Environmental Health Perspectives·Chunying ChenZhifang Chai
Feb 1, 1977·Plant Physiology·C N Giannopolitis, S K Ries

❮ Previous
Next ❯

Citations

Jul 17, 2015·Biological Trace Element Research·Natalia PawlasSławomir Kasperczyk
Apr 8, 2016·Ecotoxicology and Environmental Safety·Carlucio Rocha Dos SantosRita De Cássia Oliveira Da Costa Mattos
Apr 21, 2017·Environmental Science and Pollution Research International·He HuangXiaohua Teng

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.