Lean body mass index prognostic value for cardiovascular events in patients with coronary artery disease

Heart Asia
Hirofumi HiokiTakehiro Morita

Abstract

Little is known about the relationship between body composition indicators, including body mass index (BMI), fat mass index (FMI) and lean BMI (LBMI), and adverse outcomes after percutaneous coronary intervention (PCI) in Asian populations. The aim of this study was to clarify this relationship. The SHINANO registry is a prospective, observational, multicenter cohort registry that enrolled 1923 consecutive patients with coronary heart disease (CHD) from August 2012 to July 2013; 66 patients were excluded because of missing data. We evaluated 1857 patients with CHD who underwent PCI (aged 70±11 years; 23% women; BMI 23.8±3.5 kg/m(2); LBMI 18.3±1.8 kg/m(2); FMI 5.4±2.2 kg/m(2)). Patients were divided into three groups, based on BMI, LBMI and FMI tertiles, to assess the prognostic value of the three indicators. The primary endpoint was major adverse cardiac events (MACE), including all cause death, non-fatal myocardial infarction and ischaemic stroke at 1 year. Over a 1 year follow-up period (1776 patients, 95.6%), the cumulative MACE incidence was 8.7% (161 cases). Using Kaplan-Meier analysis, the MACE incidence was significantly higher in patients with lower BMI values (13.4-22.2 kg/m(2)) (p=0.002) and lower LBMI values (11.6-17...Continue Reading

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Citations

Oct 25, 2016·Circulation Journal : Official Journal of the Japanese Circulation Society·Sung Keun ParkJu Young Jung
May 10, 2018·Journal of the American Heart Association·Jose R Medina-InojosaFrancisco Lopez-Jimenez
Aug 18, 2020·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Chendi CuiAkira Sekikawa
Dec 20, 2018·International Journal of Environmental Research and Public Health·Shirine KhazemMarwan El Ghoch
Jul 25, 2017·European Psychiatry : the Journal of the Association of European Psychiatrists·J-H LeeJ Y Jung
Nov 18, 2020·JCI Insight·Debbie S ThompsonRobert H J Bandsma
Feb 24, 2021·Journal of Cachexia, Sarcopenia and Muscle·Hyuktae KwonSu Hwan Cho

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Methods Mentioned

BETA
X-ray

Software Mentioned

Statistical Package for Social Sciences

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