Lean muscle mass in classic or ovulatory PCOS: association with central obesity and insulin resistance

Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association
F M MarioP M Spritzer

Abstract

This age-matched case-control study assessed total and segmental lean muscle mass in classic or ovulatory polycystic ovary syndrome (PCOS) patients and investigated whether lean mass is associated with hormone and metabolic features. Participants underwent anthropometric and clinical evaluation. Habitual physical activity was assessed with a digital pedometer, and body composition by dual-energy X-ray absorptiometry. Laboratory measurements included total cholesterol, cholesterol fractions, triglycerides, glucose, total serum testosterone, serum insulin, estradiol, luteinizing hormone, and SHBG. Energy intake was calculated using a food frequency questionnaire. Classic PCOS patients had higher body mass index (BMI), waist circumference, testosterone and lipid accumulation product values than ovulatory PCOS and controls. Energy consumption, homeostasis model assessment index, SHBG, free androgen index and triglycerides, total and trunk lean mass were higher only in classic PCOS women vs. controls. Arm, leg, trunk, total or limb lean masses were not correlated with hormone levels in any of the groups. However, in PCOS women lipid accumulation product was positively correlated with total (r=0.56, p=0.001), trunk (r=0.59, p=0.001),...Continue Reading

Citations

Sep 27, 2012·The Journal of Clinical Endocrinology and Metabolism·Erica T WangKirsten Bibbins-Domingo
Nov 29, 2014·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Gislaine Satyko KogureRosana Maria Dos Reis
Apr 27, 2016·Ageing Research Reviews·Karine PerreaultIsabelle J Dionne
Jan 26, 2018·Clinical Endocrinology·Flora BacopoulouEfthymios Deligeoroglou
Nov 21, 2015·Medicine and Science in Sports and Exercise·Gislaine Satyko KogureRosana Maria Dos Reis
Jul 3, 2020·The Journal of Clinical Endocrinology and Metabolism·Maryam KazemiMarla E Lujan
Feb 18, 2020·World Journal of Diabetes·Chantal Anifa AmisiPaolo Pozzilli
Dec 22, 2020·Revista brasileira de ginecologia e obstetrícia : revista da Federação Brasileira das Sociedades de Ginecologia e Obstetrícia·Gislaine Satyko KogureRosana Maria Dos Reis
Jan 21, 2021·Journal of Functional Morphology and Kinesiology·Grei SheleDiana Speelman
Jan 8, 2019·The Journal of the American Osteopathic Association·Diana L Speelman
Apr 16, 2021·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Maryam KazemiPhilip D Chilibeck

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