PMID: 9663796Jul 15, 1998Paper

Learning disability and epilepsy. 1, towards common outcome measures

Seizure : the Journal of the British Epilepsy Association
M Kerr, Colin A Espie

Abstract

A major component of the population of people who have epilepsy are people with a learning disability. As a group, such individuals often have complex epilepsy which is refractory to treatment. Current available measures to assess the outcomes of therapeutic interventions in epilepsy are based on seizure frequency, seizure severity and quality-of-life measures, but have not been validated in people with a learning disability. Thus, we do not know if such measures of outcome serve the needs of this group. This review examines how able we are to assess the efficacy of our interventions to control epilepsy in people with learning disability. It is suggested that a standard data set is necessary as the basis of the assessment of any therapeutic intervention. Central components of this data set would encompass a definition of important characteristics of an individual, a description of their epilepsy and an assessment of the impact of their condition on both their own and their carer's health. The approach to obtaining this information should employ a methodology which can allow for environmental influences.

References

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Citations

Jan 31, 2004·Epilepsy & Behavior : E&B·Kevin KellyMartin J Brodie
May 21, 1998·Pharmacology & Therapeutics·J A Hannah, M J Brodie
Jul 15, 1998·Seizure : the Journal of the British Epilepsy Association·C A EspieG Baker
Nov 18, 2000·Journal of Intellectual Disability Research : JIDR·C Bowley, M Kerr
Apr 16, 2002·Epilepsia·Kevin KellyMartin J Brodie
Nov 16, 2006·Epilepsia·Ennapadam S Krishnamoorthy
Mar 24, 2009·Epilepsy & Behavior : E&B·Michael P KerrBernd Huber
May 23, 2006·Epilepsy & Behavior : E&B·Willeke van BlarikomAd Th G van Gennep
Jun 17, 2009·Journal of Intellectual Disability Research : JIDR·M KerrR A Wallace
Jun 16, 2001·Seizure : the Journal of the British Epilepsy Association·P CrawfordUNKNOWN Parke Davis Clinical Trials Group
Dec 9, 2008·Seizure : the Journal of the British Epilepsy Association·Christine ColeAnnabelle Dudley
Dec 17, 2008·Seizure : the Journal of the British Epilepsy Association·Janine BeavisMichael Kerr
Apr 24, 2016·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·S Kothare, J Kaleyias
Sep 4, 2015·The Cochrane Database of Systematic Reviews·Cerian F JacksonMichael Kerr
Mar 7, 2019·Acta neurologica Belgica·Anika KleistMartin Winterholler
May 23, 2020·Neuropsychiatric Disease and Treatment·Eva PipanHelena Gauffin

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