Learning modulates the ensemble representations for odors in primary olfactory networks

Proceedings of the National Academy of Sciences of the United States of America
Kevin C DalyJ G Hildebrand

Abstract

Recent evidence suggests that odor-driven responses in the insect antennal lobe (AL) can be modified by associative and nonassociative processes, as has been shown in the vertebrate olfactory bulb. However, the specific network changes that occur in response to olfactory learning remain unknown. To characterize changes in AL network activity during learning, we developed an in vivo protocol in Manduca sexta that allows continuous monitoring of neural ensembles and feeding behavior over the course of olfactory conditioning. Here, we show that Pavlovian conditioning produced a net recruitment of responsive neural units across the AL that persisted after conditioning. Recruitment only occurred when odor reliably predicted food. Conversely, when odor did not predict food, a net loss of responsive units occurred. Simultaneous measures of feeding responses indicated that the treatment-specific patterns of neural recruitment were positively correlated with changes in the insect's behavioral response to odor. In addition to recruitment, conditioning also produced consistent and profound shifts in the temporal responses of 16% of recorded units. These results show that odor representations in the AL are dynamic and related to olfactory ...Continue Reading

References

Jun 1, 1992·Journal of Comparative Psychology·K L LofdahlJ Hirsch
May 1, 1987·Experimental Neurology·S J Goldberg, D G Moulton
Jun 1, 1973·Psychological Bulletin·R E Lubow
Jun 1, 1983·Journal of Comparative Psychology·M E BittermanS Schäfer
Jan 1, 1994·Behavioral and Neural Biology·D A Wilson, R M Sullivan
Jan 1, 1997·Annual Review of Neuroscience·Y Liu, R H Edwards
Aug 14, 1997·Nature·K M KendrickS Ohkura
Oct 20, 1999·Nature Neuroscience·L M Kay, G Laurent
Oct 26, 1999·Science·G Laurent
Dec 22, 1999·Nature·M Stopfer, G Laurent
Mar 4, 2000·Learning & Memory·N Schweighofer, M A Arbib
Aug 16, 2000·Cell·L B VosshallR Axel
Feb 13, 2001·Journal of Insect Physiology·K C DalyB H Smith
Apr 3, 2001·Annual Review of Neuroscience·G LaurentH D Abarbanel

❮ Previous
Next ❯

Citations

Jul 26, 2006·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·P PeeleC G Galizia
May 11, 2013·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Marie R Clifford, Jeffrey A Riffell
Apr 25, 2007·Nature Reviews. Neuroscience·Alex C Keene, Scott Waddell
Feb 29, 2008·Proceedings of the National Academy of Sciences of the United States of America·Jeffrey A RiffellJohn G Hildebrand
Jul 28, 2010·Proceedings of the National Academy of Sciences of the United States of America·John G Hildebrand
Aug 2, 2011·Integrative and Comparative Biology·Jeffrey A Riffell
Dec 11, 2007·Annual Review of Entomology·Peter Kloppenburg, Alison R Mercer
May 18, 2007·Annual Review of Neuroscience·Leslie B Vosshall, Reinhard F Stocker
May 4, 2012·Journal of Neurophysiology·Andrew M DacksAlan J Nighorn
Mar 2, 2005·PLoS Biology·Fernando GuerrieriMartin Giurfa
Oct 31, 2008·PLoS Biology·Wilder Doucette, Diego Restrepo
Jun 15, 2007·PloS One·Hidehiro Watanabe, Makoto Mizunami
Feb 18, 2010·PloS One·Judith ReinhardCharles Claudianos
Jul 7, 2011·PloS One·Andreas Simon BrandstaetterChristoph Johannes Kleineidam
Aug 21, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Patricia C FernandezBrian H Smith
Feb 5, 2013·Trends in Neurosciences·Martin Giurfa
Oct 4, 2011·Progress in Neurobiology·Joshua P MartinJohn G Hildebrand
Jun 3, 2011·Current Opinion in Neurobiology·Nitin Gupta, Mark Stopfer
May 11, 2010·Physica D. Nonlinear Phenomena·Sungwoo AhnDavid Terman
May 26, 2009·Journal of Neuroscience Methods·Erich M StaudacherKevin C Daly
Apr 1, 2008·Trends in Biotechnology·Glen C RainsDon Kulasiri
Nov 7, 2006·Current Opinion in Neurobiology·Xu Liu, Ronald L Davis
Sep 5, 2009·The Journal of Comparative Neurology·Basil El JundiJoachim Schachtner
Nov 22, 2012·The European Journal of Neuroscience·Fernando F LocatelliBrian H Smith
Jun 12, 2012·The Journal of Comparative Neurology·Xin-Cheng ZhaoBente G Berg
Jun 23, 2011·The European Journal of Neuroscience·Lisa RathPaul Szyszka
Jan 28, 2010·The European Journal of Neuroscience·Michael DenkerRandolf Menzel
Nov 16, 2004·Trends in Neurosciences·Ralph J Greenspan, Bruno van Swinderen
Nov 2, 2005·Progress in Neurobiology·William B KristanW Otto Friesen
Sep 27, 2005·Journal of Insect Physiology·Shunpeng WangMandyam V Srinivasan
May 20, 2014·Journal of Physiology, Paris·F GuidobaldiP G Guerenstein
Sep 29, 2004·Neuron·Ronald L Davis
Sep 21, 2011·Neurobiology of Learning and Memory·Chihiro Sato MatsumotoMakoto Mizunami
Aug 27, 2009·Current Biology : CB·Nicolas Y MasseGregory S X E Jefferis

❮ Previous
Next ❯

Related Concepts

Related Feeds

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.

Related Papers

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Patricia C FernandezBrian H Smith
Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology
P PeeleC G Galizia
The European Journal of Neuroscience
Michael DenkerR Menzel
© 2022 Meta ULC. All rights reserved