PMID: 8464879Apr 1, 1993Paper

Learning selectively increases protein kinase C substrate phosphorylation in specific regions of the chick brain

Proceedings of the National Academy of Sciences of the United States of America
F S SheuA Routtenberg

Abstract

The effect of imprinting, an early form of exposure learning, on the phosphorylation state of the protein kinase C substrates myristoylated alanine-rich C-kinase substrate (MARCKS) and protein F1/43-kDa growth-associated protein (F1/GAP-43) was studied in two regions of the chick forebrain. One region, the intermediate and medial part of the hyperstriatum ventrale (IMHV), is probably a site of long-term memory; the other, the wulst, contains somatic sensory and visual projection areas. After imprinting, a significant increase in MARCKS protein phosphorylation was observed in the left IMHV but not the right IMHV. No significant alteration in F1/GAP-43 was observed in IMHV. MARCKS was resolved into two acidic components of pI approximately 5.0 and approximately 4.0. Phosphorylation of the pI approximately 5.0 MARCKS but not the pI approximately 4.0 MARCKS was significantly altered by imprinting. The partial correlation between preference score (an index of learning) and phosphorylation, holding constant the effect of approach activity during training, was significant only for the pI approximately 5.0 MARCKS in the left IMHV. A significant negative partial correlation between preference score and F1/GAP-43 phosphorylation in the r...Continue Reading

References

May 25, 1979·Brain Research·G HornP P Bateson
Nov 1, 1991·Biological Reviews of the Cambridge Philosophical Society·J J Bolhuis
Aug 29, 1990·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·G Horn
Oct 15, 1990·The Journal of Comparative Neurology·T Shimizu, H J Karten
Dec 3, 1990·Brain Research·R BurchuladzeS P Rose
Mar 1, 1990·Brain Research. Developmental Brain Research·M W Brown, G Horn
Jul 1, 1989·Brain Research. Brain Research Reviews·D J Linden, A Routtenberg
Apr 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·B J McCabe, G Horn
Apr 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·J K WangP Greengard
May 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·K A AlbertP Greengard
Nov 1, 1974·Animal Behaviour·P P Bateson, J B Jaeckel
Feb 25, 1972·Brain Research·J D Delius, K Bennetto
May 1, 1966·Biological Reviews of the Cambridge Philosophical Society·P P Bateson
Sep 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·W C WuP Greengard

❮ Previous
Next ❯

Citations

Jun 3, 2008·Experimental Brain Research·Revaz O SolomoniaGabriel Horn
Dec 1, 1994·The International Journal of Biochemistry·R Sandhir, K D Gill
Sep 1, 1994·Pharmacology, Biochemistry, and Behavior·S Miller, J M Wehner
Nov 1, 1995·Pharmacology, Biochemistry, and Behavior·P A SerranoM R Rosenzweig
Jan 1, 1993·Brain Research. Brain Research Reviews·P A Colley, A Routtenberg
Jan 1, 1996·Brain Research. Molecular Brain Research·P J MebergA Routtenberg
Jun 1, 1996·Brain Research. Molecular Brain Research·P J MebergA Routtenberg
Oct 16, 2003·Brain Research. Molecular Brain Research·Julio M AzcurraGustavo Ch Paratcha
Apr 15, 2000·Physiology & Behavior·C H Parsons, L J Rogers
Nov 24, 1999·Brain Research. Developmental Brain Research·T A McIntyreI A Shibley
Jul 31, 1998·Trends in Neurosciences·G Horn
Feb 22, 2000·Behavioural Brain Research·B J McCabe, A U Nicol
Apr 1, 1997·Progress in Neuro-psychopharmacology & Biological Psychiatry·E A Van der Zee, B R Douma
Apr 1, 1997·Progress in Neuro-psychopharmacology & Biological Psychiatry·X Noguès
Sep 1, 1997·Neuroscience·R O SolomoniaG Horn
Feb 5, 1998·Brain Research. Cognitive Brain Research·R A WhitechurchG L Sedman
Sep 30, 1998·The European Journal of Neuroscience·A U NicolG Horn
Nov 22, 1994·Proceedings of the National Academy of Sciences of the United States of America·B J McCabe, G Horn
May 2, 2007·Neuroreport·Shinji YamaguchiKoichi J Homma
Jun 22, 2000·Proceedings of the National Academy of Sciences of the United States of America·A RouttenbergU Namgung
Feb 19, 2000·Proceedings of the National Academy of Sciences of the United States of America·J J BolhuisE A Van Der Zee
Jul 19, 2014·Neuroscience and Biobehavioral Reviews·Sanne Moorman, Alister U Nicol
Aug 8, 2009·Neurotoxicology and Teratology·Joseph YanaiTheodore A Slotkin
Jan 9, 2013·Development, Growth & Differentiation·Tomoharu NakamoriHiroko Ohki-Hamazaki

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Brain Research. Molecular Brain Research
P J MebergA Routtenberg
Proceedings of the National Academy of Sciences of the United States of America
B J McCabe, G Horn
Proceedings of the National Academy of Sciences of the United States of America
B J McCabe, G Horn
© 2021 Meta ULC. All rights reserved