Learning sensory maps with real-world stimuli in real time using a biophysically realistic learning rule

IEEE Transactions on Neural Networks
M A Sánchez-MontañésP J Verschure

Abstract

We present a real-time model of learning in the auditory cortex that is trained using real-world stimuli. The system consists of a peripheral and a central cortical network of spiking neurons. The synapses formed by peripheral neurons on the central ones are subject to synaptic plasticity. We implemented a biophysically realistic learning rule that depends on the precise temporal relation of pre- and postsynaptic action potentials. We demonstrate that this biologically realistic real-time neuronal system forms stable receptive fields that accurately reflect the spectral content of the input signals and that the size of these representations can be biased by global signals acting on the local learning mechanism. In addition, we show that this learning mechanism shows fast acquisition and is robust in the presence of large imbalances in the probability of occurrence of individual stimuli and noise.

References

Jun 9, 2005·IEEE Transactions on Neural Networks·Derek Harter, Robert Kozma
Jun 27, 2015·Cognitive Neuroscience·Ivan Herreros, P F Verschure

Citations

Oct 20, 1977·Journal of Mathematical Biology·T J Sejnowski
Jan 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·T F Freund, V Meskenaite
Apr 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·G S Stent
Mar 1, 1994·Trends in Neurosciences·A M Thomson, J Deuchars
Nov 1, 1995·Neural Computation·A J Bell, T J Sejnowski
Aug 1, 1993·Current Opinion in Neurobiology·N M Weinberger
Jan 7, 1993·Nature·T V Bliss, G L Collingridge
Mar 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·N M WeinbergerB Lepan
Jun 13, 1996·Nature·R Baddeley
May 1, 1995·Neural Computation·P KönigW Singer
Jan 10, 1997·Science·L F AbbottS B Nelson
Mar 28, 1998·Science·M P Kilgard, M M Merzenich
Apr 8, 1998·Annual Review of Neuroscience·D V Buonomano, M M Merzenich
Apr 29, 1998·Annual Review of Physiology·J MageeD Johnston
Jun 6, 1998·Neural Computation·M TsodyksH Markram
Feb 7, 2001·Current Opinion in Neurobiology·J Z Tsien
Apr 19, 2000·Neural Computation·M A Sánchez-MontañésP König
Jun 9, 2000·Annual Review of Neuroscience·W Schultz, A Dickinson
Jun 9, 2000·Annual Review of Neuroscience·S J MartinR G Morris
Aug 10, 2000·Neural Networks : the Official Journal of the International Neural Network Society·K P Körding, P König
Dec 1, 1949·The Journal of Physiology·C O HEBB, R H NIMMO-SMITH
Dec 8, 1978·Brain Research·J P KellyS Kennedy

Related Concepts

Neurons
Action Potentials
Structure of Cortex of Kidney
Synapses
Neuronal
Receptive Field
Auditory Area
Cerebral Cortex
Adrenal Cortex

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Sexual Dimorphism in Neurodegeneration

There exist sex differences in neurodevelopmental and neurodegenerative disorders. For instance, multiple sclerosis is more common in women, whereas Parkinson’s disease is more common in men. Here is the latest research on sexual dimorphism in neurodegeneration

HLA Genetic Variation

HLA genetic variation has been found to confer risk for a wide variety of diseases. Identifying these associations and understanding their molecular mechanisms is ongoing and holds promise for the development of therapeutics. Find the latest research on HLA genetic variation here.

Super-resolution Microscopy

Super-resolution microscopy is the term commonly given to fluorescence microscopy techniques with resolutions that are not limited by the diffraction of light. Here are the latest discoveries pertaining to super-resolution microscopy.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.

Brain Lower Grade Glioma

Low grade gliomas in the brain form from oligodendrocytes and astrocytes and are the slowest-growing glioma in adults. Discover the latest research on these brain tumors here.

CD4/CD8 Signaling

Cluster of differentiation 4 and 8 (CD8 and CD8) are glycoproteins founds on the surface of immune cells. Here is the latest research on their role in cell signaling pathways.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.