Learning Task-Related Activities From Independent Local-Field-Potential Components Across Motor Cortex Layers

Frontiers in Neuroscience
Gonzalo Martín-VázquezTomoki Fukai

Abstract

Motor cortical microcircuits receive inputs from dispersed cortical and subcortical regions in behaving animals. However, how these inputs contribute to learning and execution of voluntary sequential motor behaviors remains elusive. Here, we analyzed the independent components extracted from the local field potential (LFP) activity recorded at multiple depths of rat motor cortex during reward-motivated movement to study their roles in motor learning. Because slow gamma (30-50 Hz), fast gamma (60-120 Hz), and theta (4-10 Hz) oscillations temporally coordinate task-relevant motor cortical activities, we first explored the behavioral state- and layer-dependent coordination of motor behavior in these frequency ranges. Consistent with previous findings, oscillations in the slow and fast gamma bands dominated during distinct movement states, i.e., preparation and execution states, respectively. However, we identified a novel independent component that dominantly appeared in deep cortical layers and exhibited enhanced slow gamma activity during the execution state. Then, we used the four major independent components to train a recurrent network model for the same lever movements as the rats performed. We show that the independent comp...Continue Reading

References

Dec 1, 1967·The Bulletin of Mathematical Biophysics·R Plonsey, D B Heppner
Oct 1, 1983·Brain Research·G BuzsákiC H Vanderwolf
Nov 1, 1995·Neural Computation·A J Bell, T J Sejnowski
Aug 18, 2000·Neural Networks : the Official Journal of the International Neural Network Society·A Hyvärinen, E Oja
Feb 13, 2001·Trends in Neurosciences·G D BrownT J Sejnowski
Jul 7, 2001·Neural Computation·A HyvärinenM Inki
Mar 11, 2003·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·R W Guillery, S M Sherman
Mar 11, 2004·Journal of Neurophysiology·Jose M HurtadoKaren A Sigvardt
Dec 17, 2008·Proceedings of the National Academy of Sciences of the United States of America·Adriano B L TortNancy J Kopell
Aug 28, 2009·Neuron·David Sussillo, L F Abbott
Oct 7, 2009·Proceedings of the National Academy of Sciences of the United States of America·Christiaan P J de Kock, Bert Sakmann
Nov 20, 2009·Nature·Laura Lee ColginEdvard I Moser
Jan 23, 2010·Journal of Computational Neuroscience·Valeri A MakarovOscar Herreras
May 14, 2010·Journal of Neurophysiology·Adriano B L TortNancy Kopell
Jun 11, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Michel Le Van QuyenJerome Engel
Oct 12, 2010·Trends in Cognitive Sciences·Ryan T Canolty, Robert T Knight
Feb 26, 2011·Frontiers in Neuroscience·Matthijs A A van der MeerA David Redish
Sep 29, 2011·Frontiers in Systems Neuroscience·Julia MakarovaOscar Herreras
Oct 11, 2011·Neuron·Shigeyoshi Fujisawa, György Buzsáki
Dec 14, 2011·Neuron·Yoshinao Kajikawa, Charles E Schroeder
Apr 13, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Antonio Fernández-RuizOscar Herreras
May 19, 2012·Nature Reviews. Neuroscience·György BuzsákiChristof Koch
Sep 13, 2012·Frontiers in Human Neuroscience·Bernadette C M van WijkAndreas Daffertshofer
Nov 2, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Takufumi YanagisawaYukiyasu Kamitani
Jan 2, 2013·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Aapo Hyvärinen
Jan 11, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Bryan M HooksGordon M G Shepherd
Feb 15, 2013·Frontiers in Computational Neuroscience·Antonio Fernández-Ruiz, Oscar Herreras
Jun 21, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Yoshikazu IsomuraTomoki Fukai
Sep 27, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Antonio Fernández-RuizOscar Herreras
Nov 10, 2013·Nature·Kenneth D Harris, Thomas D Mrsic-Flogel
Nov 22, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jun IgarashiTomoki Fukai
Feb 27, 2014·Nature Reviews. Neuroscience·György Buzsáki, Kenji Mizuseki

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