Learning to fear suffocation: a new paradigm for interoceptive fear conditioning

Psychophysiology
Meike PappensIlse Van Diest

Abstract

The present study aimed to establish a new interoceptive fear conditioning paradigm. The conditioned stimulus (CS) was a flow resistor that slightly obstructs breathing; the unconditional stimulus (US) was a breathing occlusion. The paired group (N = 21) received 6 acquisition trials with paired CS-US presentations. The unpaired group (N = 19) received 6 trials of unpaired CS-US presentations. In the extinction phase, both groups were administered 6 CS-only trials. Measurements included startle eyeblink response, electrodermal responses, and self-reported US expectancy. In the paired group, startle blink responses were larger during CS compared to intertrial interval during acquisition and extinction. Electrodermal and US expectancies were larger for the paired than for the unpaired group during acquisition, but not during extinction. The present paradigm successfully established interoceptive fear conditioning with panic-relevant stimuli.

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Citations

Jul 17, 2014·Current Opinion in Supportive and Palliative Care·Kyle T S Pattinson, Miriam J Johnson
Jun 29, 2014·Respiratory Physiology & Neurobiology·Jonas ZamanIlse Van Diest
Oct 8, 2014·Respiratory Physiology & Neurobiology·Jonas ZamanIlse Van Diest
Nov 18, 2015·Psychosomatic Medicine·Jonas ZamanIlse Van Diest
Oct 16, 2015·Behavior Therapy·Mathias SchroijenIlse Van Diest
Jan 28, 2015·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Meike PappensIlse Van Diest
Dec 8, 2015·Frontiers in Behavioral Neuroscience·Franziska LabrenzSigrid Elsenbruch
Sep 10, 2014·Psychophysiology·Sarah Miller, Paul W Davenport
Jan 21, 2015·Neuroscience and Biobehavioral Reviews·Jonas ZamanIlse Van Diest
Oct 19, 2016·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Erik CeunenIlse Van Diest
Sep 13, 2016·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Jonas ZamanJohan W S Vlaeyen
Oct 22, 2016·Psychophysiology·Georgiana JuravleAndreas von Leupoldt
Jun 23, 2019·Psychophysiology·Ilse Van Diest
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May 28, 2019·Frontiers in Physiology·Yafei TanAndreas von Leupoldt
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May 5, 2018·Biological Psychiatry : Cognitive Neuroscience and Neuroimaging·Danielle C DeVilleW Kyle Simmons
Jun 10, 2018·Biological Psychiatry : Cognitive Neuroscience and Neuroimaging·Elischa KrauseChristiane A Pané-Farré

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