PMID: 1211957Nov 1, 1975Paper

Lecithin/sphingomyelin ratio in hypopharyngeal aspirate of newborn infants

Archives of Disease in Childhood
P A BarrJ D Baum

Abstract

The lecithin/sphingomyelin (L/S) ratio was measured in the hypopharyngeal aspirate of 41 newborn infants. In 20 without respiratory distress the ratio within 24 hours from birth ranged from 1.5 to 5.8 with a mean value of 3.3. In 6 with 'transient tachypnoea of the newborn' the ratio ranged from 2.0 to 6.7 with a mean value of 3.2. In 15 infants with idiopathic respiratory distress syndrome (RDS) the ratio ranged from 0.9 to 2.1 with a mean value of 1.4. In 14 of these infants the ratio within 24 hours from birth was 1.7 or less. One infant with a higher ratio and severe RDS is described in detail. Serial hypopharyngeal aspirate L/S ratios were determined in the infants with RDS. There was a possible trend toward the earlier attainment of a ratio of 2.0 in infants who received continuous distending airway pressure compared with infants who did not.

References

Jan 1, 1974·Gynecologic Investigation·J M JimenezJ M Johnston
Sep 1, 1974·American Journal of Obstetrics and Gynecology·L GluckW N Keidel
Oct 1, 1974·Archives of Disease in Childhood·J D Baum, N R Roberton
Feb 1, 1971·American Journal of Obstetrics and Gynecology·L GluckW N Spellacy
Sep 1, 1971·Journal of Applied Physiology·J Lempert, P T Macklem
Apr 1, 1966·American Journal of Diseases of Children·M E AveryG Brumley
May 1, 1959·A.M.A. Journal of Diseases of Children·M E AVERY, J MEAD
Feb 1, 1965·The Journal of Pediatrics·F H ADAMSA SCUDDER

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.