PMID: 9446820Apr 4, 1998Paper

Lectin histochemistry reveals the appearance of M-cells in Peyer's patches of SCID mice after syngeneic normal bone marrow transplantation

The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society
R SharmaE Adam

Abstract

Peyer's patches in the intestinal mucosa are characterized by the presence of several lymphatic follicles and interfollicular T-cell regions. Luminal antigens are transported across the intestinal epithelium to stimulate the Peyer's patch pre-B-cells in the follicles that proliferate and migrate to distant sites. Evidence suggests that antigen priming of B-lymphocytes is responsible for the number and location of Peyer's patches during postnatal life, but little is known about the histogenesis of Peyer's patches and their overlying membranous (M) cells. To examine whether T- and B-lymphocytes in Peyer's patches have an influence on M-cell generation, we studied the development of Peyer's patches and M-cells in severe combined immunodeficient (SCID) mice reconstituted with bone marrow cells from normal syngeneic mice. Our experiments demonstrate that the donor bone marrow cells in the host scid mice repopulate to form single (primary) follicles and aggregates of lymphoid nodules, the Peyer's patches. Use of the lectins Anguilla anguilla (AAA) and Ulex europaeus I (UEA-I) as positive markers of mouse Peyer's patch M-cells revealed that M-cells develop in the dome epithelium overlying the single primary follicles and Peyer's patch...Continue Reading

References

Oct 1, 1992·Physiological Reviews·J P Kraehenbuhl, M R Neutra
Nov 1, 1989·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·J PlendlU Schumacher
Feb 10, 1983·Nature·G C BosmaM J Bosma
Nov 1, 1993·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·M A ClarkB H Hirst
Jan 1, 1996·Annual Review of Immunology·M R NeutraJ P Kraehenbuhl
Jun 1, 1996·Histochemistry and Cell Biology·R SharmaU Schumacher
Aug 1, 1996·Trends in Microbiology·T C Savidge

❮ Previous
Next ❯

Citations

May 26, 2005·Immunology Letters·Franziska Roth-WalterErika Jensen-Jarolim
Jan 29, 2000·Immunology·E C LavelleD T O'Hagan
Nov 7, 2007·The Journal of Experimental Medicine·Tomonori NochiHiroshi Kiyono
Oct 18, 2000·Gut·C Nicoletti
Jun 2, 2010·Acta Histochemica Et Cytochemica·Hirohiko Iwatsuki, Masumi Suda
Jun 19, 2007·Proceedings of the National Academy of Sciences of the United States of America·Tomonori NochiHiroshi Kiyono
Apr 29, 2014·Histochemistry and Cell Biology·Maria MastrodonatoDomenico Ferri
Nov 3, 2010·Journal of Drug Targeting·Barbara C Baudner, Derek T O'Hagan
Feb 24, 2016·Cell and Tissue Research·Tetsuya HondoHisashi Aso
Dec 18, 2015·Proceedings of the National Academy of Sciences of the United States of America·Christopher J DayMichael P Jennings
Feb 20, 2007·JPEN. Journal of Parenteral and Enteral Nutrition·Yoshinori FujimuraRobert L Owen
Sep 5, 2006·Research in Veterinary Science·Takashi KanayaTakahiro Yamaguchi
Jul 25, 2009·Expert Review of Vaccines·Yoshikazu Yuki, Hiroshi Kiyono
Jan 5, 2011·American Journal of Physiology. Gastrointestinal and Liver Physiology·Tetsuya HondoHisashi Aso
Jun 17, 2008·American Journal of Physiology. Gastrointestinal and Liver Physiology·Takashi KanayaHisashi Aso

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society
M A ClarkB H Hirst
The Journal of Veterinary Medical Science
Chung Hyun KimChanhee Chae
© 2021 Meta ULC. All rights reserved