Left atrial appendage morphology in patients with suspected cardiogenic stroke without known atrial fibrillation

PloS One
Miika KorhonenMikko Taina

Abstract

The left atrial appendage (LAA) is the typical origin for intracardiac thrombus formation. Whether LAA morphology is associated with increased stroke/TIA risk is controversial and, if it does, which morphological type most predisposes to thrombus formation. We assessed LAA morphology in stroke patients with cryptogenic or suspected cardiogenic etiology and in age- and gender-matched healthy controls. LAA morphology and volume were analyzed by cardiac computed tomography in 111 patients (74 males; mean age 60 ± 11 years) with acute ischemic stroke of cryptogenic or suspected cardiogenic etiology other than known atrial fibrillation (AF). A subgroup of 40 patients was compared to an age- and gender-matched control group of 40 healthy individuals (21 males in each; mean age 54 ± 9 years). LAA was classified into four morphology types (Cactus, ChickenWing, WindSock, CauliFlower) modified with a quantitative qualifier. The proportions of LAA morphology types in the main stroke group, matched stroke subgroup, and control group were as follows: Cactus (9.0%, 5.0%, 20.0%), ChickenWing (23.4%, 37.5%, 10.0%), WindSock (47.7%, 35.0%, 67.5%), and CauliFlower (19.8%, 22.5%, 2.5%). The distribution of morphology types differed significantly ...Continue Reading

References

Aug 1, 1991·Stroke; a Journal of Cerebral Circulation·P A WolfW B Kannel
Oct 22, 1987·The New England Journal of Medicine·R D Mosteller
Feb 1, 1996·The Annals of Thoracic Surgery·J L Blackshear, J A Odell
Jul 26, 2006·Circulation Journal : Official Journal of the Japanese Circulation Society·Hidenobu OkuyamaIsao Kubota
Nov 14, 2006·Journal of Cardiovascular Electrophysiology·Sheng-Hsiung ChangShih-Ann Chen
Oct 2, 2007·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Shalini Bansil, Halima Karim
Jun 17, 2010·Journal of Cardiovascular Electrophysiology·Yan WangAndrea Natale
Jul 29, 2010·Journal of Cardiovascular Electrophysiology·Roy BeinartMoussa Mansour
Nov 29, 2011·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Daniel T WalkerKaren P Phillips
Feb 2, 2012·Circulation. Arrhythmia and Electrophysiology·Ross J HunterRichard J Schilling
Sep 14, 2012·The Journal of International Medical Research·A-W ShiX-Q Kong
Oct 30, 2012·Journal of the Neurological Sciences·Daniel J MillerPanayiotis D Mitsias
Dec 1, 2012·The International Journal of Cardiovascular Imaging·Hwan-Cheol ParkYoung-Hoon Kim
Feb 7, 2013·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Takehiro KimuraKeiichi Fukuda
Oct 1, 2013·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Irfan M KhurramHugh Calkins
Oct 15, 2013·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Matteo AnselminoFiorenzo Gaita
Dec 20, 2013·Circulation·Alan S GoUNKNOWN American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Feb 14, 2014·Circulation. Cardiovascular Imaging·Masayoshi YamamotoKazutaka Aonuma
Jun 26, 2014·The New England Journal of Medicine·Tommaso SannaUNKNOWN CRYSTAL AF Investigators

❮ Previous
Next ❯

Citations

Dec 29, 2015·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Woo Kyo JeongOh Young Bang
Jan 19, 2016·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Jonathan P Piccini
May 26, 2016·The New England Journal of Medicine·Jeffrey L Saver
Jan 17, 2017·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Yuki MatsumotoAtsushi Tashiro
Apr 7, 2019·Cardiovascular Engineering and Technology·Dongjie JiaLucy T Zhang
Oct 21, 2015·Current Cardiology Reports·Krittapoom AkrawinthawongScott Wayne Ferreira
Sep 24, 2016·Journal of Neurology, Neurosurgery, and Psychiatry·Shadi YaghiRichard A Bernstein
Aug 4, 2018·Texas Heart Institute Journal·Indranill Basu Ray, Sumit K Shah
Jul 4, 2020·The Egyptian Heart Journal : (EHJ) : Official Bulletin of the Egyptian Society of Cardiology·Mohammed ElzeneiniAhmed El Mahmoudy Nayel
Nov 22, 2018·Frontiers in Cardiovascular Medicine·Indranill Basu-RayAbdi Rasekh
Oct 4, 2019·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Nabeela KarimTom Wong
Aug 16, 2017·The International Journal of Cardiovascular Imaging·Yukina HirataMasataka Sata
Feb 2, 2021·International Journal of Cardiology·Katarzyna Dudzińska-SzczerbaJakub Baran
Nov 28, 2018·Computers in Biology and Medicine·Hrvoje LeventićAleksandra Pižurica
Jul 22, 2021·Journal of Cardiovascular Electrophysiology·Fabrizio RosatiStefano Benussi

❮ Previous
Next ❯

Software Mentioned

CauliFlower
EmbodeteCT
CAREDose4D
SPSS
ChickenWing
WindSock
IDS5

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Acute Stroke

A stroke occurs when blood supply to the brain is interrupted depriving the brain of oxygen and nutrients. This feed focuses cerebrovascular accidents including ischemic and paralytic stroke.

Anti-Arrhythmic Drug Therapies

Anti-arrhythmic drugs are used to prevent abnormal heart rhythms. These medications are used in conditions including, ventricular tachycardia, ventricular fibrillation and atrial fibrillation. Discover the latest research on anti-arrhythmic drug therapies here.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Cardiovascular Diseases: Risk Factors

Cardiovascular disease is a significant health concern. Risk factors include hypertension, obesity, dyslipidemia and smoking. Women who are postmenopausal are at an increased risk of heart disease. Here is the latest research for risk factors of cardiovascular disease.

Cardiogenic Shock

Cardiogenic shock is a devastating consequence of acute myocardial infarction and is associated with an extremely high mortality. Here is the latest research.