Left atrial appendage obliteration in atrial fibrillation patients undergoing bioprosthetic mitral valve replacement

Herz
X P MinXu Meng

Abstract

Left atrial appendage (LAA) obliteration is a proven stroke-preventive measure for patients with nonvalvular atrial fibrillation (AF). However, the efficacy of LAA obliteration for patients with AF after bioprosthetic mitral valve replacement (MVR) remains unclear. This study aimed to estimate the efficacy of LAA obliteration in preventing embolism and to investigate the predictors of thromboembolism after bioprosthetic MVR. We retrospectively studied 173 AF subjects with bioprosthetic MVR; among them, 81 subjects underwent LAA obliteration using an endocardial running suture method. The main outcome measure was the occurrence of thrombosis events (TEs). The mean follow-up time was 40 ± 17 months. AF rhythm was observed in 136 patients postoperatively. The incidence rate of TEs was 13.97 % for postoperative AF subjects; a dilated left atrium (LA; > 49.5 mm) was identified as an independent risk factor of TEs (OR = 10.619, 95 % CI = 2.754-40.94, p = 0.001). For postoperative AF patients with or without LAA, the incidence rate of TEs was 15.8 % (9/57) and 12.7 % (10/79; p = 0.603), respectively. The incidence rate of TEs was 2.7 % (1/36) and 4.2 % (2/48) for the subgroup patients with a left atrial diameter of < 49.5 mm, and 38.1...Continue Reading

References

Feb 1, 1996·The Annals of Thoracic Surgery·J L Blackshear, J A Odell
Jun 1, 1997·The Annals of Thoracic Surgery·M LynchS D Clements
Aug 10, 2000·Journal of the American College of Cardiology·E S KatzI Kronzon
Jun 13, 2001·JAMA : the Journal of the American Medical Association·B F GageM J Radford
Oct 3, 2003·Journal of the American College of Cardiology·Miguel Angel García-FernándezJacobo Silva
Dec 21, 2005·American Journal of Hypertension·Marcello ChinaliRichard B Devereux
Feb 9, 2007·Journal of Cardiovascular Electrophysiology·Soufian T AlmahameedAndrea Natale
Apr 3, 2007·Journal of the American College of Cardiology·Peter B SickDavid R Holmes
Aug 25, 2007·European Heart Journal·Seiji HabaraOsamu Matsuda
Feb 19, 2008·Journal of the American College of Cardiology·Ythan H Goldberg
Feb 26, 2008·Journal of the American College of Cardiology·Brett Burstein, Stanley Nattel
Apr 12, 2008·Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology·Christian KnackstedtPatrick Schauerte
May 10, 2013·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Maximilian Y EmmertSacha P Salzberg
Mar 1, 2014·Cardiac Electrophysiology Clinics·Faisal F Syed, Paul A Friedman

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Citations

Nov 12, 2019·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Elio Martín GutiérrezGregorio Laguna

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