Left atrial function in volume versus pressure overloaded left atrium

The International Journal of Cardiovascular Imaging
Michael Y HeneinPer Lindqvist

Abstract

Left atrial (LA) pressure and volume overload both result in cavity enlargement and complications. LA volume has been shown to predict such complications, but it does not reflect myocardial function, which can be accurately assessed using myocardial deformation measurements. We hypothesized that volume overloaded LA have maintained myocardial function compared to pressure overloaded ones. We tested this hypothesis in 44 patient (mean age 62 ± 12 years) with LA volume overload (LAVOL) due to severe mitral regurgitation (MR) with no indirect signs of elevated left ventricular (LV) filling pressures based on Doppler measured isovolumic relaxation time >60 ms. We compared them with 24 (mean age 64 ± 12 years) patient with LA pressure overload (LAPOL) who proved to have PCWP >15 mmHg on right heart catheterization. Twenty-seven healthy controls (mean age 57 ± 10 years) constituted a control group. Patients with LAVOL had larger LA volumes, higher LV ejection fraction, global LV strain (LVGLS) and transmitral and pulmonary veins flow velocities (p < 0.05) and better LA atrial strain rate (LASR) function compared to LAPOL (p < 0.001). In LAVOL, the LASR during atrial contraction (LASRa) was lower than in controls (p < 0.05) indicating...Continue Reading

References

Jun 1, 1995·British Heart Journal·K WangR H Anderson
Jan 29, 1999·Heart·M Y Henein, D G Gibson
Nov 7, 2001·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·W LiM Y Henein
Feb 12, 2002·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Miguel A QuiñonesUNKNOWN Doppler Quantification Task Force of the Nomenclature and Standards Committee of the American Society of Echocardiography
Feb 4, 2009·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Sherif F NaguehArturo Evangelista
Mar 10, 2009·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Sherif F NaguehArturo Evangelisa
Jan 5, 2011·International Journal of Cardiology·M LisiS Mondillo
Nov 18, 2011·International Journal of Cardiology·Mark HeneinPer Lindqvist
Jun 5, 2013·European Heart Journal Cardiovascular Imaging·Patrizio LancellottiUNKNOWN Scientific Document Committee of the European Association of Cardiovascular Imaging
Mar 25, 2014·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Maria J VieiraBernard J Gersh
Jun 28, 2014·Stroke; a Journal of Cerebral Circulation·Jorge PagolaCarlos A Molina
Jul 18, 2014·Current Opinion in Cardiology·Darryl P Leong, Hisham Dokainish
Jul 18, 2014·Current Opinion in Cardiology·Fang FangCheuk-Man Yu

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Citations

Dec 21, 2020·Clinical Physiology and Functional Imaging·Ibadete BytyçiMichael Y Henein

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