Left atrial mechanical function and stiffness in patients with nondipper hypertension: A speckle tracking study

Clinical and Experimental Hypertension : CHE
Mehmet DemirAhmet Yıldırım

Abstract

Nondipper hypertension is associated with increased cardiovascular morbidity and mortality. Speckle tracking echocardiography is a novel and promising tool for detecting early changes in left atrial (LA) myocardial dysfunction. Our aim was to evaluate the LA mechanical function and stiffness in nondipper hypertensive patients by two-dimensional speckle tracking echocardiography strain parameters. This study included 80 hypertensive patients. Hypertensive patients were divided into two groups: 50 dipper patients (29 male, mean age 51.5 ± 8 years) and 30 nondipper patients (17 male, mean age 50.6 ± 5.4 years). LA volume indices, mitral annular velocities, and global longitudinal LA strain were measured. The ratio of E/e' to LA strain was used as an index of LA stiffness. Patients with nondipper hypertension showed increased LA volume indices and decreased LA global strain (25.3 ± 5.5 vs. 39.6 ± 9.9%, P < 0.001). LA stiffness was increased in patients with nondipper than in the dipper subjects (0.41 ± 0.15 vs. 0.19 ± 0.14, P < 0.001), and LA strain and LA stiffness were related to LA volume indices. Patients with nondipper hypertension have decreased LA global strain and increased stiffness, in comparison with dipper group. LA sti...Continue Reading

References

Jul 1, 1984·The American Journal of Cardiology·M A WeberF A Wyle
Dec 1, 2005·International Journal of Cardiology·Hye-Sun SeoNamsik Chung
Feb 7, 2006·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Roberto M LangUNKNOWN European Association of Echocardiography, European Society of Cardiology
Jul 19, 2008·Blood Pressure Monitoring·Sante D PierdomenicoFranco Cuccurullo
Mar 10, 2009·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Sherif F NaguehArturo Evangelisa
Oct 8, 2009·Circulation. Cardiovascular Imaging·Mustafa KurtSherif F Nagueh
Apr 5, 2011·Journal of Cardiovascular Electrophysiology·Tomoko Machino-OhtsukaKazutaka Aonuma
Nov 18, 2011·International Journal of Cardiology·Mark HeneinPer Lindqvist
Nov 28, 2012·Journal of cardiovascular ultrasound·Yeonyee E YoonGoo-Yeong Cho
Jan 30, 2015·The International Journal of Cardiovascular Imaging·Flavio D'AscenziSergio Mondillo

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.