Left Atrial Remodeling Assessed by Cardiac MRI after Conversion from Conventional Hemodialysis to In-Centre Nocturnal Hemodialysis.

Journal of Nephrology
Tamryn K LawAndrew T Yan

Abstract

Left atrial (LA) volume is a well-established cardiovascular prognosticator in patients with end-stage renal disease. Although dialysis intensification is associated with left ventricular mass regression, there are limited data regarding LA remodeling. Using cardiac magnetic resonance imaging (CMR), we examined changes in LA size and function relative to ventricular remodeling and cardiac biomarkers after dialysis intensification. In this prospective 2-centre cohort study, 37 patients receiving conventional hemodialysis (CHD, 4 h/session, 3×/week) were converted to in-centre nocturnal hemodialysis (INHD 7-8 h/session, 3×/week); 30 patients remained on CHD. CMR and biomarkers were performed at baseline and repeated at 52 weeks. After 52 weeks, there were no significant changes in the LA volumes or LA ejection fraction (EF) within either the CHD or INHD group, and no significant differences between the two groups. Correlations existed between changes in LA and LV end-diastolic volume index (EDVi, Spearman's r = 0.69, p < 0.001), LA and LV end-systolic volume index (ESVi, r = 0.44, p = 0.001), LAEF and LVEF (r = 0.28, p = 0.04), LA and RV EDVi (r = 0.51, p < 0.001), LA and RV ESVi (r = 0.29, p = 0.039), and LA ESVi and LV mass ind...Continue Reading

References

Dec 14, 1999·International Journal of Cardiac Imaging·O RodevanH Ihlen
Sep 8, 2001·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·N G BellengerD J Pennell
May 11, 2006·Journal of Hypertension·Giovanni TripepiCarmine Zoccali
Mar 16, 2007·Journal of the American Society of Nephrology : JASN·Giovanni TripepiCarmine Zoccali
Sep 20, 2007·JAMA : the Journal of the American Medical Association·Bruce F CulletonBraden J Manns
Nov 27, 2007·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Sangeetha SatyanRajiv Agarwal
Jan 5, 2008·Journal of the American College of Cardiology·Grace Casaclang-VerzosaTeresa S M Tsang
Apr 3, 2009·Clinical Journal of the American Society of Nephrology : CJASN·Ann BugejaMarc Goldstein
Nov 26, 2010·The New England Journal of Medicine·Glenn M ChertowAlan S Kliger
Apr 3, 2012·Current Cardiology Reports·Michael Y C TsangTeresa S M Tsang
Mar 19, 2013·Arquivos brasileiros de cardiologia·Silvio Henrique BarberatoRoberto Pecoits-Filho
May 3, 2013·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Jeanette Schulz-MengerEike Nagel
Jan 7, 2015·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Roberto M LangJens-Uwe Voigt

❮ Previous
Next ❯

Citations

Jul 20, 2019·Journal of Nephrology·Laura TapoiAdrian Covic
Sep 6, 2020·Current Opinion in Nephrology and Hypertension·Emily J See, Kevan R Polkinghorne
Feb 20, 2019·Journal of Nephrology·Richard B ThompsonUNKNOWN Alberta Kidney Disease Network

❮ Previous
Next ❯

Related Concepts

Related Feeds

Biomarkers for Cardiovascular Risk Assessment

Sensitive and accurate biomarkers used in cardiovascular risk prediction can potentially be used to manage the risk of cardiovascular disease. Discover the latest research on Biomarkers for Cardiovascular Risk Assessment here. Discover the latest research on Biomarkers for Cardiovascular Risk Assessment here.

Cardiac Remodeling

Cardiac remodeling in response to a myocardial infarction is characterized by progressive ventricular dilatation, cardiac hypertrophy, fibrosis, and deterioration of cardiac performance. Discover the latest research on Cardiac Remodeling here.