Left Atrial Strain as a Predictor of New-Onset Atrial Fibrillation in Patients With Heart Failure.

JACC. Cardiovascular Imaging
Jin Joo ParkThomas H Marwick

Abstract

This study sought to identify whether left atrial strain can predict new-onset atrial fibrillation (NOAF) in patients with heart failure (HF) and sinus rhythm. Both HF and atrial fibrillation have common risk factors, and HF is a risk factor for the development of atrial fibrillation and vice versa. Among 4,312 consecutive patients with acute HF from 3 tertiary hospitals, 2,461 patients with sinus rhythm and peak atrial longitudinal strain (PALS) were included in the study. Reduced PALS was defined as PALS ≤18%, and the primary endpoint was 5-year NOAF. During a 5-year follow-up, 397 (16.1%) patients developed NOAF. Patients with reduced PALS had higher NOAF than their counterparts (18.2% vs. 12.7%; p < 0.001). After adjustment for significant covariates, we identified 6 independent predictors of NOAF, including age >70 years (hazard ratio [HR]: 1.50; 95% confidence interval [CI]: 1.12 to 2.00), hypertension (HR: 1.45; 95% CI: 1.10 to 1.91), left atrial volume index ≥40 ml/m2 (HR: 2.03; 95% CI: 1.48 to 2.77), PALS <18% (HR: 1.60; 95% CI: 1.18 to 2.17), HF with preserved ejection fraction (HR: 1.47; 95% CI: 1.11 to 1.95), and no beta-blocker prescription at discharge (HR: 1.48; 95% CI: 1.14 to 1.92). A weighted score based on th...Continue Reading

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Citations

Mar 3, 2021·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Jin Joo ParkHee-Joon Bae
Mar 23, 2021·Current Treatment Options in Cardiovascular Medicine·Pedro CovasAndrew D Choi
Apr 30, 2021·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Martin EichenlaubAmir Jadidi
Jun 8, 2021·Circulation Journal : Official Journal of the Japanese Circulation Society·Byung Joo Sun, Jae-Hyeong Park
Jun 13, 2021·European Heart Journal Cardiovascular Imaging·Matteo LisiMichael Y Henein
Jul 1, 2021·Journal of the American Heart Association·Jae-Hyeong ParkGoo-Yeong Cho
Jul 19, 2021·JACC. Cardiovascular Imaging·Philipp E BartkoGeorg Goliasch
May 17, 2021·Journal of Cardiovascular Electrophysiology·Jayson R BamanJane E Wilcox
Sep 23, 2021·Obesity Surgery·Jakub StrzelczykGrzegorz Styczyński
Jul 20, 2020·JACC. Cardiovascular Imaging·Allan L KleinJay Ramchand
Oct 10, 2020·JACC. Cardiovascular Imaging·Thomas H Marwick, Y Chandrashekhar

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