Left or right kidney in hand-assisted donor nephrectomy? A randomized controlled trial

Transplantation
Robert C MinneeMirza M Idu

Abstract

There is an ongoing discussion in living renal transplantation whether the right or the left donor nephrectomy is to be preferred if both kidneys are equal, due to the lack of prospective studies. A prospective single-center randomized trial was conducted from April 2002 to September 2006, in which 60 eligible consecutive donors were randomized to either left-sided or right-sided hand-assisted laparoscopic donor nephrectomy (HALDN). Primary endpoint was operation time. Secondary endpoints were donor morbidity, warm ischemia time, delayed graft function, urological complications, quality of life, and graft survival. Median operating time for left-sided HALDN (180 min) was significantly longer compared with right-sided HALDN (150 min; P=0.021). There were no conversions in both groups. There were no major intra- or postoperative complications. One-year graft survival rate was 96% in the left group versus 93% in the right group (P=0.625, log rank). Operating time of HALDN of the right kidney is significantly shorter than HALDN of the left kidney. No differences were detected in complication rates and graft survival between left and right-sided donor nephrectomy.

References

Aug 10, 1995·The New England Journal of Medicine·P I TerasakiS Takemoto
Sep 6, 2000·Transplantation·J R LeventhalF P Stuart
Apr 27, 2001·Annals of Surgery·J F BuellJ L Flowers
Nov 22, 2001·The Journal of Urology·D A Goldfarb
Oct 24, 2002·Transplantation·May Y LindJan N M IJzermans
Mar 3, 2004·The British Journal of Surgery·S MaartenseW A Bemelman
Aug 19, 2004·Transplantation·Rebecca L TooherGuy J Maddern
Apr 26, 2005·Transplantation Proceedings·T L HustedJ F Buell
Apr 26, 2005·Transplantation Proceedings·T L HustedJ F Buell
Nov 1, 2005·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Anibal W BrancoMariana J Garcia
Nov 11, 2006·Journal of Endourology·Vladislav BargmanWilliam Goggins
Dec 13, 2006·Surgical Endoscopy·Scbastian DemyttenaereGerald M Fried
Feb 13, 2007·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·K K ClemensUNKNOWN Donor Nephrectomy Outcomes Research (DONOR) Network

❮ Previous
Next ❯

Citations

Mar 20, 2009·Transplantation·Leonienke F C DolsJan N M Ijzermans
Mar 29, 2011·Transplantation·John W HsuPeter L Abt
Jul 14, 2012·Transplantation·Karel W J KlopJan N M Ijzermans
Mar 29, 2014·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·B LaplaceJ Hubert
Jun 26, 2013·Journal of the American College of Surgeons·Marcio F ChedidPatrick G Dean
Jul 31, 2012·Actas urologicas españolas·O RodríguezH Villavicencio
Dec 17, 2011·Urology·Atul BagulMichael L Nicholson
Apr 27, 2010·European Urology·Francesco GrecoPaolo Fornara
Sep 22, 2009·Transplantation Proceedings·M K TarzamniN Nezami
Apr 24, 2010·Transplant International : Official Journal of the European Society for Organ Transplantation·Geir MjøenOle Øyen
Apr 12, 2012·BJU International·Neal Banga, David Nicol
Dec 17, 2009·Transplant International : Official Journal of the European Society for Organ Transplantation·Leonienke F C DolsJan N M Ijzermans
Jun 13, 2014·Progress in Transplantation : Official Publication, North American Transplant Coordinators Organization ... [et Al.]·Victor AlbertsRobert C Minnee
Oct 28, 2017·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Matteo RavaioliJacopo Romagnoli
Sep 9, 2021·Clinical Transplantation·Caitlin CarolanColin H Wilson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.