Left prefrontal cortex activation during sentence comprehension covaries with grammatical knowledge in children

NeuroImage
L J KnollJens Brauer

Abstract

Children's language skills develop rapidly with increasing age, and several studies indicate that they use language- and age-specific strategies to understand complex sentences. In the present experiment, functional magnetic resonance imaging (fMRI) and behavioral measures were used to investigate the acquisition of case-marking cues for sentence interpretation in the developing brain of German preschool children with a mean age of 6 years. Short sentences were presented auditorily, consisting of a transitive verb and two case-marked arguments with canonical subject-initial or non canonical object-initial word order. Overall group results revealed mainly left hemispheric activation in the perisylvian cortex with increased activation in the inferior parietal cortex (IPC), and the anterior cingulate cortex (ACC) for object-initial compared to subject-initial sentences. However, single-subject analysis suggested two distinct activation patterns within the group which allowed a classification into two subgroups. One subgroup showed the predicted activation increase in the left inferior frontal gyrus (IFG) for the more difficult object-initial compared to subject-initial sentences, while the other group showed the reverse effect. Th...Continue Reading

References

Mar 1, 1996·Brain and Language·K StromswoldS Rauch
Oct 4, 1996·Science·M A JustK R Thulborn
Mar 17, 1998·NeuroImage·K J FristonR Turner
Aug 8, 2001·Psychological Review·M M BotvinickJ D Cohen
Oct 27, 2001·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·G LohmannD Y von Cramon
Jan 5, 2002·NeuroImage·K J WorsleyA C Evans
Mar 20, 2004·Science·Peter HagoortKarl Magnus Petersson
Mar 31, 2004·NeuroImage·Michal Ben-ShacharYosef Grodzinsky
Nov 24, 2004·Trends in Cognitive Sciences·Matthew M BotvinickCameron S Carter
Dec 17, 2004·Journal of Cognitive Neuroscience·Christian J FiebachAngela D Friederici
May 4, 2005·Trends in Cognitive Sciences·Angela D Friederici
Aug 2, 2005·Trends in Cognitive Sciences·Peter Hagoort
Mar 28, 2006·Current Opinion in Neurobiology·Yosef Grodzinsky, Angela D Friederici
Apr 14, 2007·Nature Reviews. Neuroscience·Gregory Hickok, David Poeppel
Feb 15, 2008·Journal of Cognitive Neuroscience·Jens Brauer, Angela D Friederici
Mar 17, 2009·Neuroreport·Angela D FriedericiJörg Bahlmann
May 7, 2009·Proceedings of the National Academy of Sciences of the United States of America·Michiru MakuuchiAngela D Friederici
Oct 27, 2009·NeuroImage·H M van Ettinger-VeenstraM Engström
Mar 23, 2010·Brain and Language·Sharlene D NewmanThomas Burns
Mar 27, 2010·NeuroImage·Andrea Santi, Yosef Grodzinsky
Jan 1, 1997·Human Brain Mapping·O JosephsK Friston
Jun 23, 2010·Cerebral Cortex·Jens BrauerAngela D Friederici
Mar 23, 2011·NeuroImage·Jonas ObleserAngela D Friederici
Jul 12, 2011·Developmental Cognitive Neuroscience·S Christopher NuñezElizabeth R Sowell
Oct 21, 2011·Physiological Reviews·Angela D Friederici
Nov 1, 1997·Journal of Cognitive Neuroscience·C J PriceR J Wise

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Citations

Jul 31, 2013·Social Cognitive and Affective Neuroscience·Sai LiXiaolin Zhou
Jan 7, 2016·Frontiers in Psychology·Anna Strotseva-FeinschmidtThomas C Gunter
May 7, 2013·Brain and Language·Jens BrauerAngela D Friederici
Dec 30, 2014·Brain and Language·Gesa SchaadtAngela D Friederici
Dec 24, 2014·Brain Imaging and Behavior·M Claire SrokaUNKNOWN CMIND Authorship Consortium
Nov 9, 2016·Scientific Reports·Alice E MilneChristopher I Petkov
Jun 8, 2021·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Vincent HoofsRuth M Krebs
Apr 19, 2020·NeuroImage·Alexander EngeMichael A Skeide

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