Left ventricular blood flow kinetic energy after myocardial infarction - insights from 4D flow cardiovascular magnetic resonance.

Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance
Pankaj GargErica Dall'Armellina

Abstract

Myocardial infarction (MI) leads to complex changes in left ventricular (LV) haemodynamics that are linked to clinical outcomes. We hypothesize that LV blood flow kinetic energy (KE) is altered in MI and is associated with LV function and infarct characteristics. This study aimed to investigate the intra-cavity LV blood flow KE in controls and MI patients, using cardiovascular magnetic resonance (CMR) four-dimensional (4D) flow assessment. Forty-eight patients with MI (acute-22; chronic-26) and 20 age/gender-matched healthy controls underwent CMR which included cines and whole-heart 4D flow. Patients also received late gadolinium enhancement imaging for infarct assessment. LV blood flow KE parameters were indexed to LV end-diastolic volume and include: averaged LV, minimal, systolic, diastolic, peak E-wave and peak A-wave KEiEDV. In addition, we investigated the in-plane proportion of LV KE (%) and the time difference (TD) to peak E-wave KE propagation from base to mid-ventricle was computed. Association of LV blood flow KE parameters to LV function and infarct size were investigated in all groups. LV KEiEDV was higher in controls than in MI patients (8.5 ± 3 μJ/ml versus 6.5 ± 3 μJ/ml, P = 0.02). Additionally, systolic, minima...Continue Reading

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Citations

May 2, 2019·The International Journal of Cardiovascular Imaging·Bostjan BerlotJose Luis Zamorano
Mar 11, 2020·Annual Review of Biomedical Engineering·Gilles SoulatMichael Markl
Aug 21, 2019·Frontiers in Cardiovascular Medicine·Benjamin FidockPankaj Garg
Dec 31, 2019·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Warren J Manning
Jun 20, 2020·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Corina KräuterGert Reiter
Apr 20, 2019·BioMed Research International·Natasha BarkerPankaj Garg
Nov 23, 2020·Heart Failure Clinics·Aakash N GuptaMohammed S M Elbaz
Feb 7, 2021·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Philip A CorradoOliver Wieben
Feb 26, 2021·Journal of Biomechanics·Alessandra RivaEmiliano Votta
Jun 19, 2021·European Heart Journal Cardiovascular Imaging·Ahmet DemirkiranMarco J W Götte
Jul 13, 2021·Radiology. Cardiothoracic Imaging·Philip A CorradoOliver Wieben
Oct 12, 2021·Frontiers in Physiology·Sarah FrankShawn C Shadden
Jul 16, 2019··Kathleen AngFaramarz Samavati

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