Left ventricular ejection fraction as an independent predictor of poor outcome in acute intracerebral hemorrhage.

Brain and Behavior
Guang YangShiguang Zhao

Abstract

Few studies of the effect of cardiac abnormalities on acute intracerebral hemorrhage (ICH) outcomes have been published. We sought to determine whether the left ventricular ejection fraction (LVEF) is associated with the functional outcome and mortality of acute ICH patients. We conducted a retrospective study on 364 acute ICH patients from January to December 2016. The primary outcome was defined by the modified Rankin Scale and mortality at 3 months. The associations between LVEF and outcome were investigated using univariable and multivariable logistic regression models. Depressed LVEF was significantly associated with a poor functional outcome with an odds ratio [OR] of 0.966, 95% confidence interval (CI) 0.942-0.991, p = .008, and high mortality (OR 0.968 [95% CI 0.943-0.994], p = .015) at 3 months for acute ICH patients by univariate analysis. Multivariable logistic regression analysis indicated that LVEF was an independent predictor of a poor functional outcome (OR 0.961 [95% CI 0.935-0.988], p = .005) and mortality (OR 0.949 [95% CI 0.918-0.981], p = .002). The percentage of acute ICH patients with poor functional outcome (p = .005) and mortality (p = .002) was obviously higher in the group of patients with a LVEF of <5...Continue Reading

References

Nov 28, 2012·International Journal of Cardiology·Haralampos MilionisPatrik Michel
Sep 13, 2013·International Journal of Stroke : Official Journal of the International Stroke Society·J PutaalaD Strbian
Jun 9, 2016·The New England Journal of Medicine·Adnan I QureshiUNKNOWN ATACH-2 Trial Investigators and the Neurological Emergency Treatment Trials Network
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Jun 4, 2019·Stroke; a Journal of Cerebral Circulation·Tiberiu A PanaPhyo K Myint

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Citations

Apr 12, 2021·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Andrea LogginiChristos Lazaridis

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