Left ventricular hypertrophy is associated with cerebral microbleeds in hypertensive patients

Neurology
S-H LeeB-W Yoon

Abstract

Cerebral microbleeds (CMBs) are indicative of hemorrhage-prone microangiopathy and known to be closely associated with chronic hypertension. However, no studies have been undertaken on the association between left ventricular (LV) hypertrophy and the severity of CMB. One hundred two consecutive stroke patients with hypertension were examined. CMBs were counted using T2*-weighted gradient echo MRI data. With use of ordinal logistic regression analysis, the associations between LV mass index and other vascular risk factors and CMBs were analyzed. Hypertensive patients with CMBs showed a higher LV mass index than patients without. The grades of LV mass index were significantly correlated with the grades of CMB in the whole brain (p = 0.02), in the central gray matter (p < 0.01), and in the infratentorial area (p < 0.01), but not with those in the subcortical white matter. Ordinal regression analysis revealed that the LV mass index was independently associated with increased CMB severity (p = 0.01), regionally in the central gray matter (p < 0.01) and in the infratentorial area (p < 0.01), but not in the subcortical white matter (p = 0.63). After excluding patients with cerebral amyloid angiopathy, the association between the LV ma...Continue Reading

Citations

May 9, 2006·Journal of Neurology·José M Ferro
Mar 6, 2009·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Namiko OchiKatsuhiko Kohara
Mar 25, 2006·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Seung-Hoon LeeByung-Woo Yoon
May 3, 2013·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Kazuo YamashiroTakao Urabe
Jul 14, 2010·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Yusuke YakushijiKazuo Minematsu
Feb 27, 2010·La Presse médicale·Philippe Goas, Serge Timsit
Sep 22, 2009·Clinical Neurology and Neurosurgery·Tomofumi NishikawaKohsuke Yamashita
Jan 24, 2009·Lancet Neurology·Steven M GreenbergUNKNOWN Microbleed Study Group
Apr 24, 2007·Journal of the Neurological Sciences·Seung-Hoon LeeJae-Kyu Roh
Jul 5, 2007·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·David J Werring
Mar 31, 2011·Journal of Magnetic Resonance Imaging : JMRI·Jens M TheysohnElke R Gizewski
Oct 9, 2014·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Matthew Schrag, David M Greer
Oct 6, 2015·Korean journal of family medicine·Soo Hyun JangHyung-Min Kwon
Sep 1, 2007·Journal of Clinical Neurology·Beom Joon Kim, Seung-Hoon Lee
Aug 5, 2006·Cerebrovascular Diseases·Bruce OvbiageleDavid S Liebeskind
Aug 19, 2008·International Journal of Stroke : Official Journal of the International Stroke Society·Jens Fiehler
Mar 21, 2017·American Journal of Physiology. Heart and Circulatory Physiology·Zoltan UngvariCalin I Prodan
Jun 28, 2018·Journal of the American Heart Association·Elizabeth E MooreAngela L Jefferson
Jan 7, 2006·Stroke; a Journal of Cerebral Circulation·Anand Viswanathan, Hugues Chabriat
Aug 9, 2008·Stroke; a Journal of Cerebral Circulation·Yusuke YakushijiYasuo Kuroda
Jan 15, 2011·Stroke; a Journal of Cerebral Circulation·Irmhild Altmann-SchneiderJeroen van der Grond
Oct 12, 2017·Stroke; a Journal of Cerebral Circulation·Jonathan Graff-RadfordDavid S Knopman
Nov 15, 2008·Stroke; a Journal of Cerebral Circulation·Charlotte CordonnierRustam Al-Shahi Salman
Jul 9, 2020·Journal of Stroke·Andreas PapadopoulosMarios K Georgakis
Oct 18, 2020·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·M BuciucJ L Whitwell
Nov 30, 2020·Neuropathology and Applied Neurobiology·Daniel KirschenbaumKarl Frontzek
Nov 20, 2020·Stroke and Vascular Neurology·Luke DixonBrynmor Jones
Feb 27, 2017·Stroke; a Journal of Cerebral Circulation·Evgenia M FanouDaniel M Mandell

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