Abstract
We studied left ventricular performance and contractility after volume loading in lambs at 122 days (group I, n = 9) and 139 days gestational age (group II, n = 9) and in 8-day-old full-term lambs (group III, n = 7). All were mechanically ventilated; each preterm lamb was treated with surfactant to stabilize pulmonary function and the ductus arteriosus was occluded with an inflated catheter balloon. Cineangiograms, left ventricular and vascular pressures, and the isovolumetric index of contractility, first derivative of left ventricular pressure (dP/dt), were recorded before and after three successive whole blood volume infusions of 10 ml/kg (total 30 ml/kg). The left ventricular end-diastolic volume per kilogram and stroke volume per kilogram increased significantly in all groups after volume infusion; these measurements and heart rate and systemic vascular resistance did not differ significantly between the groups either before or after the infusions. The left ventricular peak dP/dt did not change significantly within the groups during the volume infusions. The left ventricular stroke work was greatest in full-term animals and increased significantly in all groups after volume infusion. Thus, the left ventricles of the preter...Continue Reading
References
Oct 22, 1979·The American Journal of Cardiology·R ZakL Bugaisky
Jul 1, 1979·Circulation·J O Parker, R B Case
Aug 1, 1979·Pediatric Research·T E Romero, W F Friedman
Aug 1, 1978·Pediatric Research·F H AdamsM Nozaki
Jun 1, 1978·Circulation Research·H S Klopfenstein, A M Rudolph
Aug 1, 1976·The American Journal of Physiology·S E KirkpatrickW F Friedman
May 11, 1975·The American Journal of Cardiology·F MahlerJ W Covell
Dec 1, 1975·The Journal of Physiology·P DaviesR Ward
Feb 1, 1976·Circulation·M A QuinonesJ K Alexander
Jan 1, 1986·Biology of the Neonate·K OguchiG C Emmanouilides
Oct 1, 1985·Pediatric Research·B G BaylenG C Emmanouilides
Sep 1, 1985·Pediatric Research·D F TeitelA M Rudolph
Feb 1, 1973·The American Journal of Cardiology·R Zak
Dec 1, 1972·Pediatric Research·E A LebowitzA M Rudolph
Mar 1, 1968·American Heart Journal·H Sandler, H T Dodge
Jul 1, 1984·Pediatric Research·J R KuipersA M Rudolph
Jan 1, 1984·American Heart Journal·B G BaylenG C Emmanouilides
Jan 1, 1984·Cardiovascular Research·A FujisawaC Kawai
Feb 1, 1984·Pediatric Research·G Lister
Feb 1, 1981·The Journal of Clinical Investigation·A JobeJ Padbury
Jan 1, 1983·Journal of the American College of Cardiology·J Ross
Jan 1, 1982·The American Journal of Physiology·I S ParkD J Driscoll
Apr 1, 1981·The American Journal of Cardiology·H G ErathJ W Hammon
Apr 1, 1981·Pediatric Research·T A RiemenschneiderD T Mason
Dec 1, 1981·Pediatric Research·J F PadburyD A Fisher
May 1, 1965·The American Journal of Physiology·S E DOWNINGT H GARDNER
Citations
Mar 1, 1991·European Journal of Pediatrics·E M SalibaJ Laugier
Apr 1, 1994·Journal of the American College of Cardiology·M M MarijianowskiA E Becker
Jan 1, 1996·Journal of the American College of Cardiology·T R KimballJ H Reuter
Jan 1, 1991·International Journal of Technology Assessment in Health Care·H T Versmold
Sep 1, 1994·Archives of Disease in Childhood. Fetal and Neonatal Edition·Y TakahashiG Takada
Oct 1, 1987·The Journal of Clinical Investigation·J PadburyJ Humme
Nov 1, 1987·European Journal of Pediatrics·H Stopfkuchen
Jan 1, 1992·The Journal of Pediatrics·L A LeeR A Meyer
Nov 1, 1987·The American Journal of Cardiology·G F ShollerA E Bauman
Oct 31, 2016·Critical Care : the Official Journal of the Critical Care Forum·J W KuiperC Ince
Jan 1, 2016·American Journal of Physiology. Heart and Circulatory Physiology·Etienne Fortin-PellerinLisa K Hornberger
Jul 17, 2020·Frontiers in Pediatrics·Etienne Fortin-PellerinLisa K Hornberger