Left ventricular, peripheral vascular, and neurohumoral responses to mental stress in normal middle-aged men and women. Reference Group for the Psychophysiological Investigations of Myocardial Ischemia (PIMI) Study

Circulation
L C BeckerP G Kaufmann

Abstract

The normal cardiovascular response to mental stress in middle-aged and older people has not been well characterized. We studied 29 individuals 45 to 73 years old (15 women, 14 men) who had no coronary risk factors, no history of coronary artery disease, and a negative exercise test. Left ventricular (LV) volumes and global and regional function were assessed by radionuclide ventriculography at rest and during two 5-minute standardized mental stress tasks (simulated public speaking and the Stroop Color-Word Test), administered in random order. A substantial sympathetic response occurred with both mental stress tests, characterized by increases in blood pressure, heart rate, rate-pressure product, cardiac index, and stroke work index and rises in plasma levels of epinephrine and norepinephrine but not beta-endorphin or cortisol. Despite this sympathetic response, LV volume increased and ejection fraction (EF) decreased secondary to an increase in afterload. The change in EF during mental stress-varied among individuals but was associated positively with changes in LV contractility and negatively with baseline EF and changes in afterload. EF decreased > 5% during mental stress in 12 individuals and > 8% in 5; 3 developed regional ...Continue Reading

References

Mar 1, 1978·Journal of Human Stress·S L Syme, C P Torfs
Dec 1, 1979·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·J LeBlancA Labrie
Jun 1, 1978·Psychosomatic Medicine·M FrankenhaeuserC G Swahn
Nov 1, 1977·The American Journal of Cardiology·K SagawaK M Bakalar
Aug 1, 1992·The American Journal of Cardiology·G IronsonG M Segall
Jan 1, 1991·Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association·J A BlumenthalJ Rodin
Oct 1, 1990·Journal of the American College of Cardiology·C N BaireyA Rozanski
Jan 1, 1989·European Journal of Applied Physiology and Occupational Physiology·Y KajiH Kuwabara
Apr 21, 1988·The New England Journal of Medicine·A RozanskiD S Berman
Jan 1, 1982·The Journal of Clinical Endocrinology and Metabolism·R F BarnesJ B Halter
Jan 25, 1980·JAMA : the Journal of the American Medical Association·J E Dimsdale, J Moss
Oct 1, 1994·International Journal of Sports Medicine·A WennlundP Arner
Jan 1, 1957·Cardiologia : bollettino della Società italiana di cardiologia·Z HEJL

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Citations

Dec 7, 2007·International Journal of Behavioral Medicine·Jessica P BrownShari R Waldstein
Nov 18, 2006·Psychopharmacology·Christine PhilippsenHartmut Schachinger
Jun 11, 2008·European Journal of Applied Physiology·Omri InbarB J Whipp
Oct 14, 2008·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Elizabeth A MartinAmir Lerman
Jan 1, 2003·Journal of the American Aging Association·Kenneth M MaddenJohn R Stratton
Feb 25, 2009·Current Cardiology Reports·Robert SouferAndrew J Yoon
Sep 21, 2005·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Matthew M BurgRobert Soufer
Jun 9, 2007·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Mustafa HassanDavid S Sheps
Mar 17, 1999·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·E S MezzacappaE S Katkin
Jun 10, 2003·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·James A ArrighiRobert Soufer
May 5, 2004·Psychological Bulletin·Sally S Dickerson, Margaret E Kemeny
Jun 27, 2002·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Ruth D LipmanJ Andrew Taylor
Jan 8, 2010·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Bert N UchinoCynthia A Berg
Jul 7, 2005·Postgraduate Medical Journal·S Vale
Sep 25, 2012·International Archives of Medicine·Gastão Luiz Fonseca Soares-FilhoAntonio Egidio Nardi
Apr 17, 2002·Circulation Journal : Official Journal of the Japanese Circulation Society·Yukio NakamuraYasushi Matsumoto
Nov 10, 2007·Psychosomatic Medicine·Kaki M YorkDavid S Sheps
May 30, 1998·Proceedings of the National Academy of Sciences of the United States of America·R SouferP Goldman-Rakic
Jul 24, 2004·Psychosomatic Medicine·Philip C StrikeAndrew Steptoe
Jan 29, 2010·European Journal of Nuclear Medicine and Molecular Imaging·Roberto SciagràDavid Antoniucci
Mar 30, 2013·Annual Review of Clinical Psychology·Mary A Whooley, Jonathan M Wong
Jul 23, 2011·Psychosomatics·Dustin Y YoonLilian Gonsalves
Oct 2, 2007·Research in Veterinary Science·A A OlkowskiB Laarveld
Feb 28, 2007·Journal of Psychosomatic Research·Dmitry M DavydovAleksandra Chicz-Demet
May 22, 2010·Pacing and Clinical Electrophysiology : PACE·Rachel LampertMatthew Burg
Jun 15, 2011·Cell Biochemistry and Function·Elizabeth A MartinAmir Lerman
Mar 4, 2011·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·L HuneaultA Tremblay
Dec 16, 1997·American Heart Journal·S SuzukiT Matsuo
Jul 22, 1998·The American Journal of Cardiology·D S ShepsP G Kaufmann

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