Left ventricular reconstruction brings benefit for patients with ischemic cardiomyopathy

Journal of Cardiac Failure
Gustavo C Aguiar RibeiroKleber G Franchini

Abstract

Optimal treatment strategies for some patients with ischemic cardiomyopathy can be unclear. We compared the outcome for patients treated with revascularization only or with additional ventricular reconstruction. We compared 74 consecutive patients with an ejection fraction <35% and a left end-systolic volume index >80 mL/m(2). All patients underwent revasularization but some received only revascularization (group 1) and some were randomized into a group that received additional ventricular reconstruction (group 2). Preoperative and postoperative ejection fraction, end-systolic volume, mitral regurgitation, mortality, heart failure (HF) symptoms, and recurrence were compared between groups. There was 1 postoperative death in group 2 (P =. 58). Preoperative ejection fraction between the groups was similar (P =. 19) but it differed significantly postoperatively (P < .001). HF class (New York Heart Association) decreased more in group 2 (group 2, 2.3 +/- 0.4 versus group 1, 1.4 +/- 0.4; P < .001). Incidence of HF recurrence and rehospitalization was significantly less in group 2 (P = .028). The postoperative development of higher-grade mitral regurgitation was greater in group 1 (147 +/- 32 mL/m(2) versus 119 +/- 25 mL/m(2), P = .0...Continue Reading

References

Feb 1, 1989·The Thoracic and Cardiovascular Surgeon·V DorF Montiglio
Feb 6, 2004·The Journal of Thoracic and Cardiovascular Surgery·Thomas S MaxeyIrving L Kron
Feb 1, 2005·The Annals of Thoracic Surgery·Atsushi YamaguchiTakashi Ino

❮ Previous
Next ❯

Citations

May 7, 2011·General Thoracic and Cardiovascular Surgery·Tadashi Isomura
Oct 2, 2007·The Journal of Thoracic and Cardiovascular Surgery·Randolph M SetserRichard D White
Aug 30, 2008·The Annals of Thoracic Surgery·Roni B PruczJohn V Conte
Mar 27, 2007·The Annals of Thoracic Surgery·Ulrik SartipyDan Lindblom
Mar 20, 2010·The Journal of Thoracic and Cardiovascular Surgery·Kay SunMark B Ratcliffe
May 29, 2009·Circulation Journal : Official Journal of the Japanese Circulation Society·Tadashi Isomura
May 12, 2021·Journal of Cardiovascular Translational Research·Jan NaarPetr Neužil

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.