Left ventricular restoration devices post myocardial infarction

Heart Failure Reviews
Tom HendriksPim van der Harst

Abstract

Even in the era of percutaneous reperfusion therapy, left ventricular (LV) remodeling after myocardial infarction (MI) leading to heart failure remains a major health concern. Contractile dysfunction of the infarcted myocardium results in an increased pressure load, leading to maladaptive reshaping of the LV. Several percutaneous transcatheter procedures have been developed to deliver devices that restore LV shape and function. The purposes of this review are to discuss the spectrum of transcatheter devices that are available or in development for attenuation of adverse LV remodeling and to critically examine the available evidence for improvement of functional status and cardiovascular outcomes.

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Clinical Trials Mentioned

NCT01614652
NCT02305602
NCT02543632
NCT02553785
NCT02931240
NCT00512005
NCT03142152
NCT00800046
NCT01899573
NCT02806570

Software Mentioned

MV
RESTOR
AccuCinch
TC
PARACHUTE
Revivent

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Cardiac Remodeling

Cardiac remodeling in response to a myocardial infarction is characterized by progressive ventricular dilatation, cardiac hypertrophy, fibrosis, and deterioration of cardiac performance. Discover the latest research on Cardiac Remodeling here.