Left ventricular systolic dyssynchrony in patients with Kawasaki disease: a real-time three-dimensional echocardiography study.

The International Journal of Cardiovascular Imaging
Haiyong WangLitao Ruan

Abstract

The left ventricular (LV) systolic dyssynchrony index (SDI) is an important prognostic indicator for many cardiovascular diseases; however, the characteristics of the SDI in patients with Kawasaki disease (KD) are unknown. In this study, we aimed to identify and quantify the SDI using real-time three-dimensional echocardiography (RT3DE) in KD patients during different phases. In addition, we intended to explore whether the SDI is associated with systolic dysfunction. Seventy consecutive KD patients and seventy age- and sex-matched controls were enrolled. The SDIs (percent of cardiac cycle) of 16 segments (16-SDI%) and 12 segments (12-SDI%) were calculated based on the defined standard deviation of each segment time from end diastole to the minimal systolic volume according to the 17-segment model (apex excluded). In the acute phase, the 16-SDI% and 12-SDI% were significantly higher in KD patients than in controls (4.40 ± 0.14 vs. 1.98 ± 0.12, P = 0.000; 3.55 ± 1.21 vs. 1.67 ± 0.93, P = 0.009, respectively), and patients with coronary artery aneurysm (CAA) exhibited higher 16-SDI% (P = 0.021) and 12-SDI% (P = 0.034) than patients without CAA. In the convalescent phase, patients with CAA still had higher 16-SDI% (P = 0.002) and 1...Continue Reading

References

Nov 29, 2002·Pediatric Cardiology·K DurongpisitkulC Kangkagate
Aug 17, 2006·Pediatrics International : Official Journal of the Japan Pediatric Society·Hiroshi YanagawaKazunori Kayaba
Nov 28, 2006·The American Journal of Cardiology·Malcolm I BurgessThomas H Marwick
Oct 2, 2007·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·G Hamilton BakerGirish S Shirali
Mar 4, 2008·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·John GorcsanUNKNOWN Heart Rhythm Society
Jan 28, 2010·The American Journal of Cardiology·Gaetano NuciforaJeroen J Bax
Sep 25, 2010·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Wei CuiDavid A Roberson
Jan 15, 2011·JACC. Cardiovascular Imaging·Stamatis KapetanakisMark J Monaghan
Sep 13, 2011·The American Journal of Cardiology·M Louisa AntoniVictoria Delgado
Jan 26, 2012·European Heart Journal Cardiovascular Imaging·Roberto M LangUNKNOWN European Association of Echocardiography
Mar 22, 2013·European Heart Journal Cardiovascular Imaging·Rachel T McCandlessShaji C Menon
May 30, 2013·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Yi YuJianping Yang
Dec 7, 2014·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Lasya GaurLowell H Frank
Mar 31, 2017·Circulation·Brian W McCrindleUNKNOWN American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Di
Sep 12, 2017·Pediatrics International : Official Journal of the Japan Pediatric Society·Ikuo HashimotoKo Shibata
Oct 5, 2018·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Carol MitchellEric J Velazquez
Nov 14, 2019·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Saurabh Malhotra

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.