Leiomyoma infarction after uterine artery embolization: a prospective randomized study comparing tris-acryl gelatin microspheres versus polyvinyl alcohol microspheres

Journal of Vascular and Interventional Radiology : JVIR
Gary P SiskinAllen Herr

Abstract

To determine the degree of leiomyoma infarction after uterine artery embolization (UAE) performed with tris-acryl gelatin microspheres or polyvinyl alcohol (PVA) microspheres. Patients determined to be candidates and scheduled for UAE were randomized prospectively to receive tris-acryl gelatin microspheres or PVA microspheres. The manufacturers' recommended technique was used for both products during the UAE procedures (including the recently described refined protocol for PVA microspheres). All patients underwent magnetic resonance (MR) imaging of the pelvis with contrast agent enhancement before and after the UAE procedure. On the postprocedural MR study, the degree of tumor infarction was assessed on postcontrast images. These findings were classified as follows: 100% infarction, 90%-99% infarction, 50%-89% infarction, and less than 50% infarction. Treatment failure was defined by enhancement of more than 10% of a patient's entire tumor burden. A total of 53 patients were enrolled in this study. Twenty-seven (mean age, 44.9 years) received PVA microspheres and 26 (mean age, 45.1 years) received tris-acryl gelatin microspheres. There were no significant differences in the preprocedural uterine volume, dominant tumor volume, l...Continue Reading

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Citations

Mar 20, 2010·Cardiovascular and Interventional Radiology·Alexandre LaurentJean-Pierre Pelage
Jun 25, 2010·Cardiovascular and Interventional Radiology·Tetsuya KatsumoriTomoya Kotani
Sep 22, 2010·Cardiovascular and Interventional Radiology·Marianne J VoogtLeo E H Lampmann
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Dec 1, 2008·Seminars in Interventional Radiology·Carin Gonsalves
Jun 2, 2011·Seminars in Interventional Radiology·Richard J T Owen
Apr 22, 2010·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Zahra MalekiRussell Vang
Jan 13, 2010·Cardiovascular and Interventional Radiology·Albert J SmeetsPaul N M Lohle
Dec 7, 2013·Cardiovascular and Interventional Radiology·Raj DasAnna-Maria Belli
Apr 10, 2013·Journal of Vascular and Interventional Radiology : JVIR·Hye Jeong ChoiJung Hyun Yoon
Mar 29, 2011·European Journal of Radiology·Jonathan V P LiawBertrand Janne d'Othée
Feb 1, 2011·Journal of Vascular and Interventional Radiology : JVIR·Valentin VerretAlexandre Laurent
Feb 13, 2010·Journal of Vascular and Interventional Radiology : JVIR·Howard B ChrismanReed A Omary
Mar 31, 2009·Journal of Vascular and Interventional Radiology : JVIR·James B Spies
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Sep 19, 2021·BJOG : an International Journal of Obstetrics and Gynaecology·A AmoahS D Quinn

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