Abstract
Leiomyosarcoma of the colon, excluding that of the rectum, is extremely rare. We report a case of leiomyosarcoma of the ascending colon with a brief review of literature. The clinical manifestations in our case were typical: abdominal pain, diarrhea, anorexia, and a palpable tumor that was firm, smooth, and mobile inspite of its bulk. Toxic features, cachexia and weight loss were less prominent. Morphologically the tumor was of dumbbell type with intracolic and extracolic components. The microscopic picture, consisting of spindle-shaped smooth-muscle cells with pleomorphism and one to three mitotic figures per high-power field, was characteristic. In the absence of local spread, a hemicolectomy was considered curative, but our patient developed extensive metastasis in 25 months. The correlation between mitotic activity of the tumor and prognosis in our case was consistent with that reported in literature.
References
Mar 1, 1977·Diseases of the Colon and Rectum·N K AstarjianG Reynoso
Sep 1, 1975·Diseases of the Colon and Rectum·R L WarkelA J Temple
Jan 1, 1975·Gastroenterologia Japonica·T YamakawaJ Shikata
May 1, 1972·Diseases of the Colon and Rectum·F Schumann
Jan 1, 1971·Journal of Surgical Oncology·T Matsuda, R E Condon
Jul 1, 1968·Diseases of the Colon and Rectum·G LeMoleG P Rosemond
Oct 3, 1966·JAMA : the Journal of the American Medical Association·V A Lookanoff, P C Tsapralis
Dec 1, 1952·Surgery, Gynecology & Obstetrics·A C BRODERSJ C STINSON
Jan 1, 1954·Annals of Surgery·D A MACKENZIEJ M WAUGH
Sep 1, 1956·The British Journal of Surgery·M LEVENE, E A MCVERRY
Jun 1, 1958·American Journal of Surgery·D F GUISTOL G BRIZZOLARA
Jun 1, 1965·American Journal of Surgery·S LEVINEL S SERFAS
Jun 1, 1955·The Surgical Clinics of North America·S F MARSHALL, J W CHERRY
Nov 1, 1961·The British Journal of Radiology·V ROGERS
Citations
Jan 1, 1983·Skeletal Radiology·V L Fornasier, D Paley
Apr 1, 1990·Diseases of the Colon and Rectum·W R Nuessle, T R Magill
Feb 1, 1990·Cancer·C ZornigS Schröder
Mar 31, 2020·World Journal of Surgical Oncology·Yun WangQian Gao
Oct 1, 1984·Gastroenterologia Japonica·A SuzukiY Kamada