Leiomyosarcoma of the Inferior Vena Cava: A Case Series and Review of the Literature

Annals of Vascular Surgery
Eyas AlkhaliliItzhak Nir

Abstract

Leiomyosarcoma of the inferior vena cava (IVC) is an exceedingly rare smooth muscle sarcoma. Approximately 300 cases have been described in the literature, and further research is needed to understand the disease and guide its management. Surgery remains the only potential curative measure. A retrospective chart review of patients who underwent surgical resection of IVC leiomyosarcoma at our institution over the past 3 years was performed. The patients were identified using a prospectively maintained database. Three patients with leiomyosarcoma of the infrahepatic IVC underwent radical resection carried out by a team of surgical oncologists and vascular surgeons. There were 2 males (66.7%) and 1 female (33.3%). Mean age at diagnosis was 60.3 years (range 43-78). Mean tumor size was 12.2 cm (range 5.6-22). The mean operative time was 320 min (range 180-421), mean estimated blood loss was 1,300 mL (100-2,000) mL, and average length of stay 8.67 days (6-12). All patients achieved grossly negative margins (R1 or R0 resections) and are alive with a mean overall survival of 21 months (range 12-30). Patient 1 was a 60-year-old man who presented with metachronous skin leiomyosarcomas at 2 different sites. He underwent PET/CT scan that ...Continue Reading

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Citations

May 29, 2016·Cirugía española·José Antonio Brizuela SanzCarlos Vaquero Puerta
Aug 21, 2018·Radiology·Iliana BednarovaThomas J Vogl
Mar 18, 2017·Journal of Biomechanical Engineering·Jeffrey M Mattson, Yanhang Zhang
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May 24, 2020·World Journal of Surgery·Elodie GaignardBernard Meunier
Dec 23, 2016·BJR Case Reports·Wan Hang Keith ChiuJoseph Kt Lee
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Aug 9, 2019·Annals of Vascular Surgery·Seonjeong JeongTae-Won Kwon
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