LekCheck: A Prospective Study to Identify Perioperative Modifiable Risk Factors for Anastomotic Leakage in Colorectal Surgery.

Annals of Surgery
Daitlin E HuismanFreek Daams

Abstract

To assess potentially modifiable perioperative risk factors for anastomotic leakage in adult patients undergoing colorectal surgery. Colorectal anastomotic leakage (CAL) is the single most important denominator of postoperative outcome after colorectal surgery. To lower the risk of CAL, the current research focused on the association of potentially modifiable risk factors, both surgical and anesthesiological. A consecutive series of adult patients undergoing colorectal surgery with primary anastomosis was enrolled from January 2016 to December 2018. Fourteen hospitals in Europe and Australia prospectively collected perioperative data by carrying out the LekCheck, a short checklist carried out in the operating theater as a time-out procedure just prior to the creation of the anastomosis to check perioperative values on 1) general condition 2) local perfusion and oxygenation, 3) contamination, and 4) surgery related factors. Univariate and multivariate logistic regression analysis were performed to identify perioperative potentially modifiable risk factors for CAL. There were 1562 patients included in this study. CAL was reported in 132 (8.5%) patients. Low preoperative hemoglobin (OR 5.40, P < 0.001), contamination of the operat...Continue Reading

References

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Citations

Mar 14, 2021·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Muriël ReudinkUNKNOWN LekCheck study group
Jan 9, 2022·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Izel OzmenUNKNOWN LekCheck Study Group
Feb 3, 2022·Science Translational Medicine·Jingjing WuXuanhe Zhao
Feb 7, 2022·International Journal of Colorectal Disease·Ruben RajanHanumant Chouhan

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