Length of illness and the gradient from positive to negative semantic priming in schizophrenic patients

Schizophrenia Research
B A MaherS Beaudette

Abstract

Schizophrenic patients, especially those with positive thought disorder, have been shown to show greater facilitation in a semantic priming task than normal controls and depressed patients. While some investigators have replicated these effects, others have not been able to do so. Differences in method and in the chronicity of the patients make it difficult to interpret the discrepancy between findings. The present study was conducted to examine the effect of length of illness (LOI) on semantic priming, a factor that might explain differences in replication success. Thirty schizophrenic patients performed a lexical decision task in a semantic priming paradigm. The LOI of this group ranged from 5 to 31 years. Facilitation in the priming task was positive for patients with short LOIs and declined to negative values in patients with long LOIs. The gradient of decline was significant. Analysis of the separate components of facilitation indicates that the decline was primarily due to a steady reduction of the speed with which patients responded to the associated word pairs; speed of response to non-associated pairs was unaffected. As this was a cross-sectional study it is not possible to determine whether the decline can be attribut...Continue Reading

References

Dec 1, 1992·Schizophrenia Research·S VinogradovG K Shenaut
Aug 1, 1990·Journal of Abnormal Psychology·T R KwapilJ P Chapman
Jan 1, 1988·Schizophrenia Research·T C ManschreckM L Schneyer
Jan 1, 1986·Schizophrenia Bulletin·M Harrow, J T Marengo
Aug 1, 1994·Journal of Abnormal Psychology·M SpitzerB A Maher

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Citations

Nov 25, 2003·Schizophrenia Research·Euphrosyne Gouzoulis-MayfrankUlrich Meincke
Sep 9, 2000·Schizophrenia Research·K R LawsA M Mortimer
Apr 6, 2006·Applied Neuropsychology·S Duke HanCynthia G Wible
Jan 27, 2011·Cognitive, Affective & Behavioral Neuroscience·Tali DitmanGina R Kuperberg
Feb 3, 2012·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Stefanie PfeiferLydia Krabbendam
Aug 27, 2015·Journal of the International Neuropsychological Society : JINS·Eric Josiah TanSusan Lee Rossell
Jan 12, 2007·NeuroImage·S Duke HanCynthia G Wible
Oct 16, 2016·Psychiatry Research·Eric Josiah TanSusan Lee Rossell
May 3, 2008·Clinical EEG and Neuroscience·M Niznikiewicz
Feb 5, 2008·The British Journal of Psychiatry : the Journal of Mental Science·E Pomarol-ClotetP J McKenna
Apr 2, 2002·The British Journal of Psychiatry : the Journal of Mental Science·Peter J Siekmeier, Ralph E Hoffman

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