Lens opacities, demographic factors and nutritional supplements in the Barbados Eye Study

International Journal of Epidemiology
M C LeskeA Schachat

Abstract

This study evaluated the association of age-related lens opacities with the use of nutritional supplements and demographic factors among 4314 black participants (> or = 40 years) in the population-based Barbados Eye Study. Lenses were classified at the slit lamp by the Lens Opacities Classification System II (LOCS II); a score > or = 2 was used to define the presence of gradable lens opacities, by type. Lens changes also included prior cataract surgery or cataract too advanced to grade. Associations with risk factors were evaluated by logistic regression analyses. The study identified 1800 individuals with lens changes in at least one eye; 229 had nuclear opacities only; 851 had cortical opacities only. Older age and indicators of lower socioeconomic status (low education and/or non-professional occupation), were positively associated with both nuclear (odds ratio [OR] = 1.90) and cortical (OR = 1.47) opacities. Women had an increased risk of cortical opacities (OR = 1.41). Regular users of nutritional supplements were less likely to have lens changes (OR = 0.78) and, specifically, cortical opacities (OR = 0.77). The association with nutritional supplements was present in those < 70 years, but not at older ages. The study suppo...Continue Reading

Citations

Dec 10, 2002·American Journal of Ophthalmology·Kristin K SnowJohanna M Seddon
May 14, 1998·Molecular Aspects of Medicine·A TaylorM Obin
Oct 31, 2001·Nutrition·A Taylor, M Hobbs
May 16, 2002·Clinical & Experimental Ophthalmology·Christine YounanElena Rochtchina
Jan 20, 1999·Proceedings of the Association of American Physicians·W G Christen
Aug 4, 2006·The British Journal of Ophthalmology·M C GrieshaberS Orgül
Jun 1, 2011·American Journal of Epidemiology·Kaziwe MollazadeganJonas F Ludvigsson
Dec 11, 2007·Ophthalmology·William G ChristenJulie E Buring
Nov 30, 1999·American Journal of Ophthalmology·C A McCartyH R Taylor
Aug 2, 2006·Experimental Eye Research·Chung-Jung Chiu, Allen Taylor
Jan 3, 2006·American Journal of Ophthalmology·Adrienne L WestSayoko E Moroi
Nov 7, 2000·International Ophthalmology Clinics·A Taylor
Nov 7, 2000·International Ophthalmology Clinics·S Y Wu, M C Leske
Jun 15, 2012·The Cochrane Database of Systematic Reviews·Milan C MathewRichard M Davis
Jan 11, 2000·Eye·H R Taylor
Jun 10, 2000·Current Opinion in Ophthalmology·R Ritch
Feb 8, 2000·Current Opinion in Ophthalmology·N G Congdon, K P West
Mar 5, 2004·Nutrition Reviews·Julie A Mares
Jun 30, 2019·JAMA Network Open·Andrew BastawrousHannah Kuper
Jan 19, 2006·British Journal of Hospital Medicine·Mandeep S Sagoo, Stephen J Tuft

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.