PMID: 18435296Apr 26, 2008Paper

Lentiviral vectors and advance in its application

Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi
Bo ChuYunming Tang

Abstract

Lentiviral vectors (Lv), known as holding lots of virtues (e.g. transfection to the dividing or non-dividing cells;large capacity of transfer gene fragments; long-term expression transfer genes; and low rate of immunological response) has come to be one of the hot-spots in gene therapy research. In this paper, taking the Lv derived from HIV-1 for example, we review the characteristics of frame, the developments and the advances in application of Lv.

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