PMID: 15218426Jun 26, 2004Paper

Leptomeningeal precursor B-cell lymphoblastic lymphoma in a child with minimal bone marrow involvement

Journal of Pediatric Hematology/oncology
Oussama AblaSheila Weitzman

Abstract

The authors report an unusual presentation of a leptomeningeal lymphoblastic lymphoma in a 6-year-old boy with headache and papilledema as the only initial manifestations. The diagnosis was confirmed by the presence of precursor B-cell lymphoblasts in the cerebrospinal fluid, with no cerebral mass and with only 9% phenotypically identical blasts in the bone marrow. This patient was treated on a high-risk ALL protocol with intensive systemic/intrathecal chemotherapy plus cranial irradiation, and he remained in complete remission 6 months after his initial diagnosis.

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Citations

Dec 1, 2006·Neurosurgical Focus·Oussama Abla, Sheila Weitzman
Jul 12, 2012·World Journal of Surgical Oncology·Xiu-fang SuiXing Yu
May 9, 2014·Journal of Neuropathology and Experimental Neurology·Caterina GianniniDiva R Salomão
Jan 18, 2006·Pediatric Blood & Cancer·Takashi TagaShigeru Ohta
Sep 13, 2006·Journal of Cutaneous Pathology·Ji-Yeon KimEun-So Lee

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