Leptospirosis among Returned Travelers: A GeoSentinel Site Survey and Multicenter Analysis-1997-2016

The American Journal of Tropical Medicine and Hygiene
Sophia G de Vries For The GeoSentinel Surveillance Network

Abstract

Leptospirosis is a potentially fatal emerging zoonosis with worldwide distribution and a broad range of clinical presentations and exposure risks. It typically affects vulnerable populations in (sub)tropical countries but is increasingly reported in travelers as well. Diagnostic methods are cumbersome and require further improvement. Here, we describe leptospirosis among travelers presenting to the GeoSentinel Global Surveillance Network. We performed a descriptive analysis of leptospirosis cases reported in GeoSentinel from January 1997 through December 2016. We included 180 travelers with leptospirosis (mostly male; 74%; mostly tourists; 81%). The most frequent region of infection was Southeast Asia (52%); the most common source countries were Thailand (N = 52), Costa Rica (N = 13), Indonesia, and Laos (N = 11 each). Fifty-nine percent were hospitalized; one fatality was reported. We also distributed a supplemental survey to GeoSentinel sites to assess clinical and diagnostic practices. Of 56 GeoSentinel sites, three-quarters responded to the survey. Leptospirosis was reported to have been most frequently considered in febrile travelers with hepatic and renal abnormalities and a history of freshwater exposure. Serology was th...Continue Reading

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Citations

Nov 6, 2018·Journal of Travel Medicine·Andrea K BoggildKevin C Kain
Nov 27, 2018·Journal of Travel Medicine·Anita E Heywood, Rogelio López-Vélez
Oct 13, 2018·Journal of Travel Medicine·Morgan Birabaharan, Stefan H F Hagmann
Nov 29, 2020·Journal of Travel Medicine·Davidson H HamerMichael Libman

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