Lesion and patient characteristics associated with malignancy after a probably benign finding on community practice mammography

AJR. American Journal of Roentgenology
Constance D LehmanStephen H Taplin

Abstract

The purpose of this study was to identify patient and lesion characteristics associated with a diagnosis of breast malignancy within 3 years of having a probably benign finding (BI-RADS category 3) on a mammogram obtained in a community radiology practice. The subjects were women 30 years old and older without breast implants or previous breast cancer who received notice of a probably benign finding on a bilateral screening mammogram between January 1, 1996, and June 30, 1999, in a community-based practice. From 82,898 mammograms, we identified 129 breast lesions designated probably benign that progressed to malignancy within 3 years of an index examination (cases) and matched them to 129 lesions designated probably benign that did not progress to malignancy within 3 years (controls). A breast imaging specialist blinded to case-control status interpreted all examinations and recorded detailed lesion descriptors according to the BI-RADS lexicon. Case lesions were more likely in patients who were older, postmenopausal, or had a strong family history of breast cancer or previous biopsy. The lesions were more likely masses with obscured, indistinct, or spiculated margins compared with control lesions (84.6% vs 66%, p = 0.03). Case ...Continue Reading

References

Feb 4, 1999·AJR. American Journal of Roentgenology·L S CaplanD L Monticciolo
Dec 5, 2000·Annals of Internal Medicine·K KerlikowskeR Ballard-Barbash
Apr 27, 2001·Radiology·I VizcaínoUNKNOWN Sceening Program Working Group
Apr 4, 2002·Radiology·Eric L RosenMary Scott Soo
Aug 20, 2002·AJR. American Journal of Roentgenology·Ximena VarasFelix Leborgne
Mar 20, 2003·Journal of the National Cancer Institute·Shagufta YasmeenSusan L Hendrix
Feb 20, 2004·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Stephen H TaplinEmily White
Oct 21, 2004·Journal of the National Cancer Institute·Stephen H TaplinWilliam E Barlow
Sep 23, 2006·Radiology·Berta M GellerUNKNOWN Breast Cancer Surveillance Consortium

❮ Previous
Next ❯

Citations

Sep 18, 2009·Journal of Digital Imaging·Ryan W WoodsElizabeth Burnside
Jan 3, 2012·Archives of Pathology & Laboratory Medicine·Michael O IdowuRaouf E Nakhleh
Mar 26, 2014·AJR. American Journal of Roentgenology·Chris Sungwon ChungRobyn L Birdwell
Dec 24, 2010·Radiology·Ryan W WoodsElizabeth S Burnside
Aug 26, 2014·Breast Cancer Research and Treatment·Stephanie K PattersonKuanwong Watcharotone
Jul 25, 2012·Seminars in Ultrasound, CT, and MR·Catherine S GiessRobyn L Birdwell
Mar 1, 2012·Journal of Clinical Ultrasound : JCU·Emel AlimogluTimur Sindel
Oct 25, 2016·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Eric PelletierJacques Brisson
Aug 20, 2016·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Aya Y MichaelsCatherine S Giess
Sep 20, 2015·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Soo-Yeon KimHye Ryoung Koo
Sep 10, 2016·The Breast Journal·Aya MichaelsCatherine S Giess

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.