PMID: 6977021Feb 1, 1982Paper

Lesion detection with single-photon emission computed tomography (SPECT) compared with conventional imaging

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
R J JaszczakR E Coleman

Abstract

We have evaluated analytically and experimentally the effectiveness of both conventional nuclear medicine imaging and single-photon emission computed tomography (SPECT) imaging to detect small photon-deficient areas (approximately the size of the system's resolution) with a relatively uniform background. The experimental model is based on the Tc-99m sulfur colloid study of the liver. The experimental data were obtained from a liver phantom containing two small photon deficient areas, nominally 1 and 1.5 cm in diameter. The liver phantom was placed in a water-filled Alderson body phantom and scanned with the cold defects located both centrally and peripherally. Lesion image contrast for both conventional and SPECT imaging is proportional to the lesion uptake ratio and is degraded by the system's finite spatial resolution and Compton-scattered photons. However, for conventional imaging the contrast is significantly degraded by the effect of radionuclide superposition (as modified by attenuation), while for SPECT imaging the contrast is essentially independent of these effects. This results in a significant increase in lesion-to-background contrast with SPECT as compared with conventional imaging. The measured SPECT image contrast...Continue Reading

Citations

Jan 1, 1987·European Journal of Nuclear Medicine·G F EdeburnD E Tow
Aug 1, 1989·Computer Methods and Programs in Biomedicine·M Ljungberg, S E Strand
Jan 1, 1989·Neurosurgical Review·B Nägele-WöhrleK Hahn
Jan 1, 1989·IEEE Transactions on Medical Imaging·D F VaslowJ A Bianco
Jan 1, 1987·International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology·K W Logan
Jan 1, 1987·International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology·D B Sodee, M Ballistrea

❮ Previous
Next ❯

Related Concepts

Related Feeds

Acute viral rhinopharyngitis

Acute viral rhinopharyngitis, also known as "common cold", is an acute, self-limiting viral infection of the upper respiratory tract involving the nose, sinuses, pharynx and larynx. Discover the latest research on acute viral rhinopharyngitis here.

Related Papers

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
R J JaszczakR E Coleman
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
D J MaceyS J DeNardo
© 2021 Meta ULC. All rights reserved