Lessons learned from molecular defects in nuclear factor kappaB dependent signaling

Microbes and Infection
Douglas R McDonaldR S Geha

Abstract

Nuclear factor (NF) kappaB is a ubiquitously expressed transcription factor that plays critical roles in normal development and inflammation. Characterization of naturally occurring defects in signaling pathways leading to activation of NFkappaB, complemented by mouse knockout models, has demonstrated the vital role of NFkappaB in normal host defense.

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Citations

Apr 29, 2008·American Journal of Respiratory Cell and Molecular Biology·Elizabeth P SampaioSteven M Holland
Aug 5, 2014·The Journal of Allergy and Clinical Immunology·Stuart E TurveyKlaus Warnatz
Mar 7, 2006·Microbes and Infection·Tom H M Ottenhoff
Oct 1, 2017·Cold Spring Harbor Perspectives in Biology·Hideo NegishiHideyuki Yanai
Mar 30, 2010·Journal of Cellular and Molecular Medicine·Amde Selassie Shifera

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