PMID: 8607217Jan 29, 1996Paper

Leucoaraiosis in patients with acute apoplexy. The Copenhagen Stroke Study

Ugeskrift for laeger
H S JørgensenT S Olsen

Abstract

Leuco-araiosis (LA) is a common finding in patients with stroke. The cause(s) of LA, risk factors and the clinical significance remains largely unknown. This prospective, community-based study of 1351 patients with acute stroke/TIA was undertaken to uncover factors of importance in the development of LA, and to assess the impact of LA on the prognosis of stroke. The diagnosis of LA was based on CT scan. Fifteen percent of the patients had LA. Age was the only factor that significantly increased the risk of LA (OR 2.4 per 10-year increase; 95% CI 1.8 to 3.1), whereas atrial fibrillation decreased the risk of LA (OR 0.26; 95% CI 0.13 to 0.52). Moderate daily alcohol consumption (one to five drinks) was associated with a reduced risk (OR 0.50; 95% CI 0.28 to 0.87), but more heavy alcohol consumption (more than five drinks) tended to increase the risk of LA (OR 1.3; 95% CI 0.5 to 3.3). LA did not influence the prognosis of stroke with regard to neurological outcome (p = 0.20), functional outcome (p = 0.47), length of hospital stay (p = 0.75), and mortality (p = 0.31). The relation between daily alcohol intake and LA seems to be U-shaped, like the relation between alcohol and coronary heart disease, alcohol and mortality, and alcoho...Continue Reading

Related Concepts

Related Feeds

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Acute Stroke

A stroke occurs when blood supply to the brain is interrupted depriving the brain of oxygen and nutrients. This feed focuses cerebrovascular accidents including ischemic and paralytic stroke.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Related Papers

Recent Developments in Alcoholism : an Official Publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism
R E LaPorteD Van Thiel
Stroke; a Journal of Cerebral Circulation
Mahmoud ZureikPierre Ducimetière
© 2021 Meta ULC. All rights reserved